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PRI-2205

 
National Institutes of Health

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Broader (1)

calcipotriene

Papers overview

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2018
2018
Calcitriol and Its Analogs Establish the Immunosuppressive Microenvironment That Drives Metastasis in 4T1 Mouse Mammary Gland Cancer
In our previous study, calcitriol and its analogs PRI-2191 and PRI-2205 stimulated 4T1 mouse mammary gland cancer metastasis… Expand
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2015
2015
Differential interference of vitamin D analogs PRI-1906, PRI-2191, and PRI-2205 with the renewal of human colon cancer cells refractory to treatment with 5-fluorouracil
This study was aimed to determine whether hypocalcemic analogs of active forms of vitamins D modulate expression of genes related… Expand
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2015
2015
Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model
In previous papers, we presented data on studies on the anticancer activity of the vitamin D3 analogs, named PRI-2191 and PRI… Expand
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2015
2015
ANTIPROLIFERATIVE AND CYTOTOXIC EFFECT OF SELECTED VITAMIN D ANALOGS ON NASAL POLYPS FIBROBLASTS AND OTHER CELLS WITH HIGHER PROLIFERATIVE POTENTIAL.
Besides well-known effect on bone and mineral metabolism vitamin D is involved in essential non-calcemic regulatory mechanisms… Expand
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2014
2014
Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment
In the present study, we evaluated the antitumor effect of two synthetic analogs of vitamin D, namely PRI-2191 [(24R)-1,24… Expand
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2013
2013
Synthesis and Biological Activity of Diastereomeric and Geometric Analogs of Calcipotriol, PRI-2202 and PRI-2205, Against Human HL-60 Leukemia and MCF-7 Breast Cancer Cells
Diastereomeric and geometric analogs of calcipotriol, PRI-2202 and PRI-2205, were synthesized as advanced intermediates from… Expand
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2013
2013
Combined colonic cancer treatment with vitamin D analogs and irinotecan or oxaliplatin.
UNLABELLED aim: The aim of this study was the evaluation of the antitumor effect of two synthetic analogs of vitamin D, PRI-2191… Expand
2013
2013
Vitamin D analogs enhance the anticancer activity of 5-fluorouracil in an in vivo mouse colon cancer model
BackgroundActive vitamin D analogs that are less toxic than calcitriol can be useful in the combined treatment of patients… Expand
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Highly Cited
2007
Highly Cited
2007
Antitumor properties of diastereomeric and geometric analogs of vitamin D3
Analogs of 1,25-dihydroxyvitamin D3 with a reversed configuration at C-1 or C-24 and E or Z geometry of the double bond at C-22… Expand
2007
2007
The antitumor effect of lowered doses of cytostatics combined with new analogs of vitamin D in mice.
Active and less toxic vitamin D analogs could be useful for clinical applications. In the present study, the antitumor effects of… Expand
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