PRI-2205
National Institutes of Health
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In our previous study, calcitriol and its analogs PRI-2191 and PRI-2205 stimulated 4T1 mouse mammary gland cancer metastasis…
This study was aimed to determine whether hypocalcemic analogs of active forms of vitamins D modulate expression of genes related…
In previous papers, we presented data on studies on the anticancer activity of the vitamin D3 analogs, named PRI-2191 and PRI…
Besides well-known effect on bone and mineral metabolism vitamin D is involved in essential non-calcemic regulatory mechanisms…
In the present study, we evaluated the antitumor effect of two synthetic analogs of vitamin D, namely PRI-2191 [(24R)-1,24…
Diastereomeric and geometric analogs of calcipotriol, PRI-2202 and PRI-2205, were synthesized as advanced intermediates from…
UNLABELLED
aim: The aim of this study was the evaluation of the antitumor effect of two synthetic analogs of vitamin D, PRI-2191…
Active vitamin D analogs that are less toxic than calcitriol can be useful in the combined treatment of patients suffering from…
Analogs of 1,25-dihydroxyvitamin D3 with a reversed configuration at C-1 or C-24 and E or Z geometry of the double bond at C-22…
Active and less toxic vitamin D analogs could be useful for clinical applications. In the present study, the antitumor effects of…