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PREMATURE CENTROMERE DIVISION

Known as: PCD, X-CHROMOSOME CENTROMERE PECULIARITY 
National Institutes of Health

Papers overview

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2004
2004
Evidence for the repeated primary non-disjunction of chromosome 21 as a result of premature centromere division (PCD)
SummaryA clinically normal 28-year-old woman had three conceptuses with trisomy 21 and one normal child. She showed minimal… 
2003
2003
Prenatal diagnosis of a rare chromosomal instability syndrome: Variegated aneuploidy related to premature centromere division (PCD)
We report complete cytogenetic data of the first successful prenatal diagnosis of the variegated aneuploidy related to premature… 
2002
2002
Association of nonsyndromic Wilms tumor with premature centromere division (PCD).
Wilms tumor was discovered in a 22-month-old otherwise healthy girl. Her pretreatment karyotype proved to be normal 46,XX with… 
Review
1999
Review
1999
Syndrome of microcephaly, Dandy-Walker malformation, and Wilms tumor caused by mosaic variegated aneuploidy with premature centromere division (PCD): report of a new case and review of the literature
AbstractWe report a male infant with multiple congenital anomalies and mosaic variegated aneuploidy; a rare cytogenetic… 
1996
1996
Premature centromere division in three unrelated families.
We describe three unrelated families with an increased frequency of cells with premature centromere division (PCD) in all of the… 
1995
1995
Premature centromere division: a possible manifestation of chromosome instability.
Retrospective analysis of "routine" chromosome preparations from 2 patients with Fanconi anemia and 2 others with ataxia… 
Review
1988
Review
1988
C-anaphases in lymphocyte cultures versus premature centromere division syndromes
SummaryDifferent cases in which chromosomes obtained from short-term lymphocyte cultures appear with separated centromeres are… 
1987
1987
Premature centromere division (PCD): a dominantly inherited cytogenetic anomaly
SummaryWe describe a family with an increased frequency of cells with premature centromere division (PCD) of all chromosomes in… 
1987
1987
Premature centromere division dominantly inherited in a subfertile family.
An increased frequency of mitoses showing premature centromere division (PCD) in every chromosome was found in lymphocyte… 
Highly Cited
1977
Highly Cited
1977
Total aneuploidy and age-related sex chromosome aneuploidy in cultured lymphocytes of normal men and women
SummaryIn PHA-cultured lymphocytes, about 8% of metaphases from 32 women were aneuploid compared to 4% of metaphases from 35 men… 
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