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POU2F1 protein, human

Known as: Oct-1, NF-A1, OTF-1 
POU domain, class 2, transcription factor 1 (743 aa, ~76 kDa) is encoded by the human POU2F1 gene. This protein plays a role in the regulation of… 
National Institutes of Health

Related topics

Related topics

14 relations
Androgen Receptor Regulation PathwayCell NucleusDNA-Binding ProteinsGenes, Regulator

Broader (1)

octamer transcription factor OTF-1

Papers overview

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Highly Cited
2009
Highly Cited
2009
Lamin B1 controls oxidative stress responses via Oct-1
Interaction of lamins with chromatin and transcription factors regulate transcription. Oct-1 has previously been shown to… 
Highly Cited
2000
Highly Cited
2000
Octamer transcription factor-1 enhances hepatic nuclear factor-1alpha-mediated activation of the human UDP glucuronosyltransferase 2B7 promoter.
The human UDP glucuronosyltransferase, UGT2B7, is expressed in the liver and gastrointestinal tract, where it catalyzes the… 
Highly Cited
1998
Highly Cited
1998
Interaction of Oct‐1 and automodification domain of poly(ADP‐ribose) synthetase
Highly Cited
1997
Highly Cited
1997
Using altered specificity Oct‐1 and Oct‐2 mutants to analyze the regulation of immunoglobulin gene transcription
Oct‐1 and Oct‐2 represent the prototypical example of related transcription factors with identical DNA recognition properties… 
Highly Cited
1996
Highly Cited
1996
The transcription factors Sp1 and Oct-1 interact physically to regulate human U2 snRNA gene expression.
The expression of human small nuclear U2 RNA genes is controlled by the proximal sequence element (PSE), which determines the… 
Highly Cited
1996
Highly Cited
1996
A soluble transcription factor, Oct-1, is also found in the insoluble nuclear matrix and possesses silencing activity in its alanine-rich domain
Expression of the human thyrotropin beta (hTSHbeta) gene is restricted to thyrotrophs, at least in part, by silencing. Using… 
Highly Cited
1995
Highly Cited
1995
The POU homeodomain transcription factor Oct-1 is essential for activity of the gonadotropin-releasing hormone neuron-specific enhancer
The mechanisms of specification of gene expression in a complex tissue such as the brain remain poorly understood. To provide a… 
Highly Cited
1992
Highly Cited
1992
Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter
Highly Cited
1991
Highly Cited
1991
The ubiquitous transcription factor Oct-1 and the liver-specific factor HNF-1 are both required to activate transcription of a hepatitis B virus promoter
The liver-specific transcription factor HNF-1 activates transcription of several mammalian hepatocyte-specific genes. The… 
Highly Cited
1990
Highly Cited
1990
Characterization of a cellular factor which interacts functionally with Oct-1 in the assembly of a multicomponent transcription complex.
Induction of transcription of the immediate-early (IE) genes of herpes simplex virus involves the assembly of a DNA-binding… 
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