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POLG2 gene

Known as: POLYMERASE, DNA, GAMMA-2, HP55, polymerase (DNA) gamma 2, accessory subunit 
 

Topic mentions per year

Topic mentions per year

1999-2016
02419992016

Related topics

Related topics

1 relation
POLG gene

Related mentions per year

Related mentions per year

1997-2018
1990200020102020
POLG2 gene
POLG gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
POLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial localization and impaired respiratory capacity.
Human mitochondrial DNA (mtDNA) is replicated and repaired by the mtDNA polymerase gamma, polγ. Polγ is composed of three… (More)
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2015
2015
Polymerase subunit gamma 2 affects porcine oocyte maturation and subsequent embryonic development.
Deoxyribonucleic acid polymerase subunit gamma (POLG) is an enzyme encoded by the mitochondrial Polg gene. Polymerase (DNA… (More)
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2013
2013
Preparation, characterization, and evaluation in vivo of Ins-SiOâ‚‚-HP55 (insulin-loaded silica coating HP55) for oral delivery of insulin.
Insulin is the most effective and durable drug in the treatment of advanced stage diabetes. However, oral delivering insulin was… (More)
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2012
2012
HP55-coated capsule containing PLGA/RS nanoparticles for oral delivery of insulin.
In this work, we designed and developed a two-stage delivery system composed of enteric capsule and cationic nanoparticles for… (More)
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2012
2012
Solvent mediated microstructures and release behavior of insulin from pH-sensitive nanoparticles.
The insulin loaded nanoparticles composed of poly (lactic-co-glycolic acid) (PLGA) and hydroxypropyl methylcellulose phthalate… (More)
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2011
2011
Biochemical analysis of human POLG2 variants associated with mitochondrial disease.
Defects in mitochondrial DNA (mtDNA) maintenance comprise an expanding repertoire of polymorphic diseases caused, in part, by… (More)
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2011
2011
175th ENMC International Workshop: Mitochondrial protein synthesis in health and disease, 25-27th June 2010, Naarden, The Netherlands.
A meeting was convened in Naarden (June 25–27th 2010) bringing together seven clinicians/clinical scientists and 11 basic… (More)
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2010
2010
Late-onset ptosis and myopathy in a patient with a heterozygous insertion in POLG2
Polymerase gamma 1 (POLG) mutations are a frequent cause of both autosomal dominant and recessive complex neurological phenotypes… (More)
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Highly Cited
2009
Highly Cited
2009
A heterozygous truncating mutation in RRM2B causes autosomal-dominant progressive external ophthalmoplegia with multiple mtDNA deletions.
Autosomal-dominant progressive external ophthalmoplegia (adPEO) is a mitochondrial disorder that is characterized by accumulation… (More)
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Highly Cited
2006
Highly Cited
2006
Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia.
DNA polymerase gamma (pol gamma ) is required to maintain the genetic integrity of the 16,569-bp human mitochondrial genome… (More)
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