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POLG2 gene

Known as: POLYMERASE, DNA, GAMMA-2, HP55, polymerase (DNA) gamma 2, accessory subunit 
National Institutes of Health

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POLG gene

Papers overview

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2013
2013
Preparation, characterization, and evaluation in vivo of Ins-SiO₂-HP55 (insulin-loaded silica coating HP55) for oral delivery of insulin.
Highly Cited
2013
Highly Cited
2013
HtrA2/Omi deficiency causes damage and mutation of mitochondrial DNA.
Highly Cited
2012
Highly Cited
2012
HP55-coated capsule containing PLGA/RS nanoparticles for oral delivery of insulin.
2012
2012
Novel preparation of PLGA/HP55 nanoparticles for oral insulin delivery
The aim of the present study was to develop the PLGA/HP55 nanoparticles with improved hypoglycemic effect for oral insulin… 
Highly Cited
2009
Highly Cited
2009
A heterozygous truncating mutation in RRM2B causes autosomal-dominant progressive external ophthalmoplegia with multiple mtDNA deletions.
Review
2008
Review
2008
Inherited mitochondrial diseases of DNA replication.
  • W. Copeland
  • Annual review of medicine
  • 2008
  • Corpus ID: 10436172
Mitochondrial genetic diseases can result from defects in mitochondrial DNA (mtDNA) in the form of deletions, point mutations, or… 
Highly Cited
2008
Highly Cited
2008
Global Identification of Myc Target Genes Reveals Its Direct Role in Mitochondrial Biogenesis and Its E-Box Usage In Vivo
The Myc oncoprotein is a transcription factor involved in a variety of human cancers. Overexpression of Myc is associated with… 
Highly Cited
2006
Highly Cited
2006
Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia.
DNA polymerase gamma (pol gamma ) is required to maintain the genetic integrity of the 16,569-bp human mitochondrial genome… 
Highly Cited
2004
Highly Cited
2004
Bioavailability and pharmacokinetics of cyclosporine A-loaded pH-sensitive nanoparticles for oral administration.
Highly Cited
1999
Highly Cited
1999
The Mitochondrial p55 Accessory Subunit of Human DNA Polymerase γ Enhances DNA Binding, Promotes Processive DNA Synthesis, and Confers N-Ethylmaleimide Resistance*
Human DNA polymerase γ is composed of a 140-kDa catalytic subunit and a smaller accessory protein variously reported to be 43–54… 
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