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POLG2 gene

Known as: POLYMERASE, DNA, GAMMA-2, HP55, polymerase (DNA) gamma 2, accessory subunit 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Mammalian mitochondrial DNA (mtDNA) is replicated by the heterotrimeric Pol γ comprised of a single catalytic subunit, encoded by… Expand
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2013
2013
Insulin is the most effective and durable drug in the treatment of advanced stage diabetes. However, oral delivering insulin was… Expand
Highly Cited
2012
Highly Cited
2012
In this work, we designed and developed a two-stage delivery system composed of enteric capsule and cationic nanoparticles for… Expand
2012
2012
The aim of the present study was to develop the PLGA/HP55 nanoparticles with improved hypoglycemic effect for oral insulin… Expand
Highly Cited
2011
Highly Cited
2011
Defects in mitochondrial DNA (mtDNA) maintenance comprise an expanding repertoire of polymorphic diseases caused, in part, by… Expand
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2010
2010
Polymerase gamma 1 (POLG) mutations are a frequent cause of both autosomal dominant and recessive complex neurological phenotypes… Expand
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Highly Cited
2008
Highly Cited
2008
The Myc oncoprotein is a transcription factor involved in a variety of human cancers. Overexpression of Myc is associated with… Expand
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Highly Cited
2006
Highly Cited
2006
DNA polymerase gamma (pol gamma ) is required to maintain the genetic integrity of the 16,569-bp human mitochondrial genome… Expand
Highly Cited
2004
Highly Cited
2004
The pH-sensitive cyclosporine A (CyA) nanoparticles were prepared by the solvent displacement method with enteric dissolved… Expand
Highly Cited
1999
Highly Cited
1999
Human DNA polymerase γ is composed of a 140-kDa catalytic subunit and a smaller accessory protein variously reported to be 43–54… Expand
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