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POLE4 gene

Known as: POLYMERASE, DNA, EPSILON-4, polymerase (DNA) epsilon 4, accessory subunit, p12 
 
National Institutes of Health

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POLD4 genePOLE gene

Papers overview

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2020
2020
Synthetic Lethality between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication
Summary Genome stability requires coordination of DNA replication origin activation and replication fork progression. RTEL1 is a… Expand
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2020
2020
Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids
Radiation-induced normal tissue toxicity often limits the curative treatment of cancer. Moreover, normal tissue relative… Expand
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2018
2018
Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis
Summary DNA polymerase ε (POLE) is a four-subunit complex and the major leading strand polymerase in eukaryotes. Budding yeast… Expand
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Highly Cited
2015
Highly Cited
2015
Frequency and phenotypic spectrum of germline mutations in POLE and seven other polymerase genes in 266 patients with colorectal adenomas and carcinomas.
In a number of families with colorectal adenomatous polyposis or suspected Lynch syndrome/HNPCC, no germline alteration in the… Expand
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2014
2014
MicroRNA and messenger RNA profiling reveals new biomarkers and mechanisms for RDX induced neurotoxicity
BackgroundRDX is a well-known pollutant to induce neurotoxicity. MicroRNAs (miRNA) and messenger RNA (mRNA) profiles are useful… Expand
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2014
2014
Title MicroRNA and messenger RNA profiling reveals new biomarkersand mechanisms for RDX induced neurotoxicity
Background: RDX is a well-known pollutant to induce neurotoxicity. MicroRNAs (miRNA) and messenger RNA (mRNA) profiles are useful… Expand
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Highly Cited
1998
Highly Cited
1998
Evolution of color exchange in QCD hard scattering
Abstract In QCD hard scattering cross sections, the color content of the underlying hard scattering evolves with a factorization… Expand
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