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POLA2 gene

Known as: polymerase (DNA) alpha 2, accessory subunit, POLA2, DNA polymerase alpha subunit B 
 
National Institutes of Health

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Genes

Papers overview

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2020
2020
Involvement of POLA2 in Double Strand Break Repair and Genotoxic Stress.
Cellular survival is dependent on the efficient replication and transmission of genomic information. DNA damage can be introduced… Expand
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2017
2017
STN1–POLA2 interaction provides a basis for primase-pol α stimulation by human STN1
Abstract The CST (CTC1–STN1–TEN1) complex mediates critical functions in maintaining telomere DNA and overcoming genome-wide… Expand
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2017
2017
Exploring the FGFR3-related oncogenic mechanism in bladder cancer using bioinformatics strategy
BackgroundAberrant activation of fibroblast growth factor receptor 3 (FGFR3) is frequently observed in bladder cancer, but how it… Expand
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Highly Cited
2016
Highly Cited
2016
Single Gene Prognostic Biomarkers in Ovarian Cancer: A Meta-Analysis
Purpose To discover novel prognostic biomarkers in ovarian serous carcinomas. Methods A meta-analysis of all single genes probes… Expand
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2016
2016
Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells
BackgroundGemcitabine is used as a standard drug treatment for non-small cell lung cancer (NSCLC), but treatment responses vary… Expand
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2016
2016
Identification of crucial regulatory relationships between long non-coding RNAs and protein-coding genes in lung squamous cell carcinoma.
PURPOSE This study aimed to analyze the relationships of long non-coding RNAs (lncRNAs) and protein-coding genes in lung squamous… Expand
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Highly Cited
2014
Highly Cited
2014
Efficient Identification of Mutated Cancer Antigens Recognized by T Cells Associated with Durable Tumor Regressions
Purpose: Cancer immunotherapy with adoptive transfer of tumor-infiltrating lymphocytes (TIL) represents an effective treatment… Expand
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2014
2014
Novel SNP improves differential survivability and mortality in non-small cell lung cancer patients
BackgroundNon-small cell lung cancer (NSCLC) is a major cause of cancer-related death worldwide due to poor patient prognosis and… Expand
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2009
2009
PolA2 is required for embryo development in Arabidopsis 1
DNA replication machinery is highly conserved in eukaryotes. DNA polymerase is essential for the synthesis of new DNA strands and… Expand
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2001
2001
E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase epsilon B-subunit gene POLE2.
The B-subunits of replicative DNA polymerases from Archaea to humans belong to the same protein family, suggesting that they… Expand
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