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PNU 120596

Known as: PNU-120596, PNU120596 
National Institutes of Health

Papers overview

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2019
2019
Discovery of fused heterocyclic carboxamide derivatives as novel α7-nAChR agonists: Synthesis, preliminary SAR and biological evaluation.
2018
2018
Positive allosteric modulators of α7* or β2* nicotinic acetylcholine receptors trigger different kinase pathways in mitochondria.
2017
2017
Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors
Human SLURP-1 is a secreted protein of the Ly6/uPAR/three-finger neurotoxin family that co-localizes with nicotinic acetylcholine… 
2016
2016
Subtype-selective nicotinic acetylcholine receptor agonists can improve cognitive flexibility in an attentional set shifting task
2015
2015
Maximizing the effect of an α7 nicotinic receptor PAM in a mouse model of schizophrenia-like sensory inhibition deficits
2013
2013
Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT1a receptor antagonist
2012
2012
Type I and II positive allosteric modulators differentially modulate agonist‐induced up‐regulation of α7 nicotinic acetylcholine receptors
Long‐term treatment with nicotine or selective α7 nicotinic acetylcholine receptor (nAChR) agonists increases the number of α7… 
2011
2011
In Search of Allosteric Modulators of α7-nAChR by Solvent Density Guided Virtual Screening
Abstract Nicotinic acetylcholine receptors (nAChR) are pentameric ligand gated ion channels whose activity can be modulated by… 
2009
2009
Local and global calcium signals associated with the opening of neuronal alpha7 nicotinic acetylcholine receptors.
2009
2009
Characterization of compounds on nicotinic acetylcholine receptor alpha7 channels using higher throughput electrophysiology
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