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PMX 205

Known as: PMX-205, PMX205 
National Institutes of Health

Papers overview

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2018
2018
Anti-inflammatory Effects of PMX205 in Mouse Macrophage Periodontitis Model.
BACKGROUND C5a receptor antagonist PMX205 is a synthetic hexapeptide capable of blocking C5a-C5a receptor (C5aR) axis by… 
2016
2016
Expression of complement C5a receptor and the viability of 4T1 tumor cells following agonist-antagonist treatment.
BACKGROUND Complement system is theoretically believed to halt the progression of tumor by the activity of C5a/CD88. Protein C5a… 
2015
2015
Blood brain barrier impairment alters the pharmacokinetic properties of the complement C5aR1 antagonist PMX205 in mouse models of neurodegeneration
2008
2008
Blockade of C5a receptors reduces astroglial inflammation in a rat SOD1G93A model of amyotrophic lateral sclerosis
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