Skip to search formSkip to main contentSkip to account menu

PMEPA1 gene

Known as: solid tumor-associated 1, PMEPA1, TRANSMEMBRANE PROSTATE ANDROGEN-INDUCED RNA 
National Institutes of Health

Related topics

Related topics

1 relation
PMEPA1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Redundant and specific roles of cohesin STAG subunits in chromatin looping and transcriptional control
Cohesin is a ring-shaped multiprotein complex that is crucial for 3D genome organization and transcriptional regulation during… 
2019
2019
PMEPA1 induces EMT via a non‐canonical TGF‐β signalling in colorectal cancer
Prostate transmembrane protein androgen induced 1 (PMEPA1) has been reported to promote cancer progression. Metastasis is the… 
Highly Cited
2018
Highly Cited
2018
Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy
It is unknown if adult human skeletal muscle has an epigenetic memory of earlier encounters with growth. We report, for the first… 
Review
2016
Review
2016
Cohesin mutations in human cancer.
Highly Cited
2014
Highly Cited
2014
TGF-β induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer
TMEPAI (transmembrane prostate androgen-induced) is amplified at genomic, transcript and protein levels in triple-negative breast… 
Highly Cited
2014
Highly Cited
2014
TMEPAI/PMEPA1 enhances tumorigenic activities in lung cancer cells
TMEPAI/PMEPA1 is a transmembrane protein that was originally identified as a prostatic RNA, the synthesis of which is induced by… 
Highly Cited
2011
Highly Cited
2011
PMEPA1 promotes androgen receptor‐negative prostate cell proliferation through suppressing the Smad3/4–c‐Myc–p21$^{{\rm Cip1}}$ signaling pathway
The PMEPA1 gene has been shown to suppress the androgen receptor (AR) and TGFβ signaling pathways and is abnormally expressed in… 
Highly Cited
2010
Highly Cited
2010
Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers
The stromal compartment is increasingly recognized to play a role in cancer. However, its role in the transition from preinvasive… 
Highly Cited
2008
Highly Cited
2008
A Feedback Loop between the Androgen Receptor and a NEDD4-binding Protein, PMEPA1, in Prostate Cancer Cells*
PMEPA1 was identified originally as a highly androgen-inducible gene with prostate-abundant expression that was restricted to… 
Highly Cited
2003
Highly Cited
2003
PMEPA1, a transforming growth factor-beta-induced marker of terminal colonocyte differentiation whose expression is maintained in primary and metastatic colon cancer.
To identify potential effectors of transforming growth factor (TGF)-beta-mediated suppression of colon cancer, we used GeneChip… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)