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PLCB3 gene

Known as: PLCB3, PHOSPHOLIPASE C, BETA-3, phospholipase C beta 3 
This gene is involved in the initiation of receptor-mediated signal transduction.
National Institutes of Health

Related topics

Related topics

7 relations
HydrolysisLipid MetabolismPLCB2 genePLCB3 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Is MYND Domain-Mediated Assembly of SMYD3 Complexes Involved in Calcium Dependent Signaling?
Macromolecular complexes are essential to intracellular signal transduction by creating signaling niches and enabling a chain of… 
2018
2018
PLCB3 Loss of Function Reduces Pseudomonas aeruginosa‐Dependent IL‐8 Release in Cystic Fibrosis
Abstract The lungs of patients with cystic fibrosis (CF) are characterized by an exaggerated inflammation driven by secretion of… 
2016
2016
Closing the gap: genetic landscape of MPN.
In this issue of Blood, Milosevic Feenstra et al1 and Cabagnols et al2 report the discovery of heterogeneous novel mutations in… 
2003
2003
In situ RNA-RNA hybridisation of phospholipase C beta 3 shows lack of expression in neuroendocrine tumours.
BACKGROUND Phospholipase C beta 3 (PLCB3) plays an important role in the signal transduction of the seven transmembrane receptors… 
2001
2001
Differentially expressed cDNAs in PLCbeta3-induced tumor suppression in a human endocrine pancreatic tumor cell line: activation of the human mismatch repair protein 3 gene.
Phospholipase Cbeta3 (PLCB3) is located to chromosome 11q13 in the vicinity of the multiple endocrine neoplasia type1 (MEN1) gene… 
1996
1996
Exclusion of the phosphoinositide-specific phospholipase Cβ3 (PLCB3) gene as a candidate for multiple endocrine neoplasia type 1
Abstract The predisposing genetic defect in multiple endocrine neoplasia type 1 has been assigned to chromosomal region 11q13… 
1996
1996
Isolation and characterization of a novel gene close to the human phosphoinositide-specific phospholipase C beta 3 gene on chromosomal region 11q13.
We describe the isolation, characterization, and genomic structure of a gene, Phospholipase C beta 3 Neighboring gene (PNG… 
1995
1995
Localization of the human phosphatidylinositol-specific phospholipase c beta 3 gene (PLCB3) within chromosome band 11q13.
1995
1995
Genomic organization and complete cDNA sequence of the human phosphoinositide-specific phospholipase C beta 3 gene (PLCB3).
1995
1995
Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-beta 3 (Plcb3), to chromosome region 19B by FISH.
A recent study using comparative mapping analysis suggests that the proximal segment of mouse chromosome 19 contains the mouse… 
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