FAQ

PLCB3 gene

Known as: PLCB3, PHOSPHOLIPASE C, BETA-3, phospholipase C beta 3 
This gene is involved in the initiation of receptor-mediated signal transduction.

Topic mentions per year

Topic mentions per year

1994-2018
012319942018

Related topics

Related topics

7 relations
HydrolysisLipid MetabolismPLCB2 genePLCB3 protein, human
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
PLCB3 gene
Hydrolysis
Signal Transduction
Lipid Metabolism
Tumor Suppression
PLCB4 gene

Papers overview

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2010
2010
Serotonin 2B receptor signaling is required for craniofacial morphogenesis and jaw joint formation in Xenopus.
Serotonin (5-HT) is a neuromodulator that plays many different roles in adult and embryonic life. Among the 5-HT receptors, 5… (More)
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2008
2008
Resveratrol attenuates thromboxane A2 receptor agonist-induced platelet activation by reducing phospholipase C activity.
Resveratrol (3,5,4'-trihydroxystilbene) is a naturally occurring compound shown to decrease the incidence of thromboembolic… (More)
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2004
2004
Angiotensin II induced upregulation of G alpha q/11, phospholipase C beta 3 and extracellular signal-regulated kinase 1/2 via angiotensin II type 1 receptor.
BACKGROUND The role of the G alpha q/11-mediated signal transduction pathway in angiotensin II (AngII) induced cardiac… (More)
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2003
2003
The ichq mutant mouse, a model for the human skin disorder harlequin ichthyosis: mapping, keratinocyte culture, and consideration of candidate genes involved in epidermal growth regulation.
Harlequin ichthyosis (HI) is a rare and usually fatal scaling skin disorder. The HI mutant mouse (ichq/ichq) has many… (More)
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2000
2000
Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C.
Activation of protein kinase C (PKC) can result from stimulation of the receptor-G protein-phospholipase C (PLCbeta) pathway. In… (More)
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1999
1999
Suppression of the neoplastic phenotype by transfection of phospholipase C beta 3 to neuroendocrine tumor cells.
The expression of phospholipase C beta 3 (PLCB3) is low or absent in several neuroendocrine neoplasias. To investigate the role… (More)
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1996
1996
Exclusion of the phosphoinositide-specific phospholipase Cβ3 (PLCB3) gene as a candidate for multiple endocrine neoplasia type 1
The predisposing genetic defect in multiple endocrine neoplasia type 1 has been assigned to chromosomal region 11q13. Our… (More)
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1995
1995
Adrenal lesion in multiple endocrine neoplasia type 1.
BACKGROUND Multiple endocrine neoplasia (MEN) type 1 is accompanied by adrenal involvement, but characteristics and clinical… (More)
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1995
1995
Genomic organization and complete cDNA sequence of the human phosphoinositide-specific phospholipase C beta 3 gene (PLCB3).
We have characterized the complete cDNA sequence, genomic structure, and expression of the human phosphoinositide-specific… (More)
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1994
1994
The phospholipase C beta 3 gene located in the MEN1 region shows loss of expression in endocrine tumours.
Oncogenesis of tumours related to multiple endocrine neoplasia type 1 (MEN1) is associated with somatic deletions involving the… (More)
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