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PLCB3 gene

Known as: PLCB3, PHOSPHOLIPASE C, BETA-3, phospholipase C beta 3 
This gene is involved in the initiation of receptor-mediated signal transduction.
National Institutes of Health

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7 relations
HydrolysisLipid MetabolismPLCB2 genePLCB3 protein, human
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Papers overview

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2016
2016
Closing the gap: genetic landscape of MPN.
In this issue of Blood, Milosevic Feenstra et al1 and Cabagnols et al2 report the discovery of heterogeneous novel mutations in… Expand
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2015
2015
Effect evaluation of cisplatin-gemcitabine combination chemotherapy for advanced non-small cell lung cancer patients using microarray data.
OBJECTIVE This study was performed to evaluate the therapeutic effect of cisplatin-gemcitabine combination chemotherapy for… Expand
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2008
2008
Multiple signals regulate phospholipase CBeta3 in human myometrial cells.
Phospholipase CB3 (PLCB3) serine(1105) (S(1105)), a substrate for multiple protein kinases, represents a potential point of… Expand
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2007
2007
Calmodulin potentiates G? activation of phospholipase C-3
Phospholipase C-β (PLC-β) isozymes (EC 3.1.4.11) hydrolyze the membrane phospholipid phosphatidylinositol-4,5-bisphosphate to… Expand
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2001
2001
Differentially expressed cDNAs in PLCbeta3-induced tumor suppression in a human endocrine pancreatic tumor cell line: activation of the human mismatch repair protein 3 gene.
Phospholipase Cbeta3 (PLCB3) is located to chromosome 11q13 in the vicinity of the multiple endocrine neoplasia type1 (MEN1) gene… Expand
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1999
1999
Suppression of the neoplastic phenotype by transfection of phospholipase C beta 3 to neuroendocrine tumor cells.
The expression of phospholipase C beta 3 (PLCB3) is low or absent in several neuroendocrine neoplasias. To investigate the role… Expand
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1996
1996
Exclusion of the phosphoinositide-specific phospholipase Cβ3 (PLCB3) gene as a candidate for multiple endocrine neoplasia type 1
Abstract The predisposing genetic defect in multiple endocrine neoplasia type 1 has been assigned to chromosomal region 11q13… Expand
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1995
1995
Genomic organization and complete cDNA sequence of the human phosphoinositide-specific phospholipase C beta 3 gene (PLCB3).
We have characterized the complete cDNA sequence, genomic structure, and expression of the human phosphoinositide-specific… Expand
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1995
1995
Localization of the human phosphatidylinositol-specific phospholipase c beta 3 gene (PLCB3) within chromosome band 11q13.
In course of the molecular characterization of a human extragonadal germ cell tumor (EGCT)-associated chromosomal translocation… Expand
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1995
1995
Assignment of the mouse homologue of a human MEN1 candidate gene, phospholipase C-beta 3 (Plcb3), to chromosome region 19B by FISH.
A recent study using comparative mapping analysis suggests that the proximal segment of mouse chromosome 19 contains the mouse… Expand
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