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PLCB3 gene

Known as: PLCB3, PHOSPHOLIPASE C, BETA-3, phospholipase C beta 3 
This gene is involved in the initiation of receptor-mediated signal transduction.
National Institutes of Health

Related topics

Related topics

7 relations
HydrolysisLipid MetabolismPLCB2 genePLCB3 protein, human
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
PLCB3 Loss of Function Reduces Pseudomonas aeruginosa‐Dependent IL‐8 Release in Cystic Fibrosis
Abstract The lungs of patients with cystic fibrosis (CF) are characterized by an exaggerated inflammation driven by secretion of… Expand
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2016
2016
Closing the gap: genetic landscape of MPN.
In this issue of Blood, Milosevic Feenstra et al1 and Cabagnols et al2 report the discovery of heterogeneous novel mutations in… Expand
2011
2011
Phospholipase Cβ3 mediates LH-induced granulosa cell differentiation.
Previous studies showed that under certain conditions LH can stimulate not only adenylate cyclase (AC) but also phospholipase C… Expand
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2007
2007
Calmodulin potentiates G? activation of phospholipase C-3
Phospholipase C-β (PLC-β) isozymes (EC 3.1.4.11) hydrolyze the membrane phospholipid phosphatidylinositol-4,5-bisphosphate to… Expand
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2001
2001
Differentially expressed cDNAs in PLCbeta3-induced tumor suppression in a human endocrine pancreatic tumor cell line: activation of the human mismatch repair protein 3 gene.
Phospholipase Cbeta3 (PLCB3) is located to chromosome 11q13 in the vicinity of the multiple endocrine neoplasia type1 (MEN1) gene… Expand
1999
1999
Suppression of the neoplastic phenotype by transfection of phospholipase C β 3 to neuroendocrine tumor cells
The expression of phospholipase C β 3 (PLCB3) is low or absent in several neuroendocrine neoplasias. To investigate the role of… Expand
1996
1996
Exclusion of the phosphoinositide-specific phospholipase Cβ3 (PLCB3) gene as a candidate for multiple endocrine neoplasia type 1
Abstract The predisposing genetic defect in multiple endocrine neoplasia type 1 has been assigned to chromosomal region 11q13… Expand
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1996
1996
Isolation and characterization of a novel gene close to the human phosphoinositide-specific phospholipase C beta 3 gene on chromosomal region 11q13.
We describe the isolation, characterization, and genomic structure of a gene, Phospholipase C beta 3 Neighboring gene (PNG… Expand
1995
1995
Localization of the human phosphatidylinositol-specific phospholipase c beta 3 gene (PLCB3) within chromosome band 11q13.
In course of the molecular characterization of a human extragonadal germ cell tumor (EGCT)-associated chromosomal translocation… Expand
1995
1995
Genomic organization and complete cDNA sequence of the human phosphoinositide-specific phospholipase C beta 3 gene (PLCB3).
We have characterized the complete cDNA sequence, genomic structure, and expression of the human phosphoinositide-specific… Expand
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