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PKP2 gene

Known as: PKP2, PLAKOPHILIN 2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Disruption of Ca2+i Homeostasis and Cx43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in PKP2-Deficient Mice.
BACKGROUND Plakophilin-2 (PKP2) is classically defined as a desmosomal protein. Mutations in PKP2 associate with most cases of… 
2016
2016
Brugada Syndrome and PKP2: Evidences and uncertainties.
2014
2014
Plakophilin 2 affects cell migration by modulating focal adhesion dynamics and integrin protein expression.
Plakophilin 2 (PKP2), a desmosome component, modulates the activity and localization of the small GTPase RhoA at sites of cell… 
2012
2012
PKP2 mutations in sudden death from arrhythmogenic right ventricular cardiomyopathy (ARVC) and sudden unexpected death with negative autopsy (SUDNA).
BACKGROUND Plakophilin2 (PKP2) is a desmosome-related protein with numerous armadillo repeats and has been linked to… 
2011
2011
Expression of Plakophilins (PKP1, PKP2, and PKP3) in Gastric Cancers
BackgroundThe importance of cell-cell junction proteins (including armadillo proteins) in tumor biology is known, but limited… 
Highly Cited
2010
Highly Cited
2010
Compound and digenic heterozygosity contributes to arrhythmogenic right ventricular cardiomyopathy.
Highly Cited
2007
Highly Cited
2007
Function of plastidial pyruvate kinases in seeds of Arabidopsis thaliana.
Pyruvate kinase (PK) catalyses the irreversible synthesis of pyruvate and ATP, which are both used in multiple biochemical… 
2006
2006
Novel mutation of plakophilin-2 associated with arrhythmogenic right ventricular cardiomyopathy.
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a disease characterized by dilatation and akinesis of the right… 
Highly Cited
2003
Highly Cited
2003
Immunohistochemical localization of plakophilins (PKP1, PKP2, PKP3, and p0071) in primary oropharyngeal tumors: correlation with clinical parameters.
Highly Cited
1999
Highly Cited
1999
Desmosomal plakophilin 2 as a differentiation marker in normal and malignant tissues.
Plakophilin 2 (PKP2) is a widespread protein which shows a remarkable dual location: On the one hand, it appears as a… 
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