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PKN3 gene
Known as:
PROTEIN KINASE N3
, PKN3
, PKNbeta
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National Institutes of Health
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Related topics
Related topics
1 relation
protein kinase Nbeta
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification.
Christopher M Browne
,
Baishan Jiang
,
+12 authors
J. Marto
Journal of the American Chemical Society
2018
Corpus ID: 54526289
Despite recent clinical successes for irreversible drugs, potential toxicities mediated by unpredictable modification of off…
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2018
2018
The interaction of p130Cas with PKN3 promotes malignant growth
Jakub Gemperle
,
Michal Dibus
,
L. Koudelková
,
Daniel Rosel
,
J. Brábek
bioRxiv
2018
Corpus ID: 53291198
Protein p130Cas constitutes an adaptor protein mainly involved in integrin signaling downstream of Src kinase. Owing to its…
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2014
2014
siRNA nanoparticles: the future of RNAi therapeutics for oncology?
S. Chou
,
A. J. Mixson
Nanomedicine
2014
Corpus ID: 23162146
siRNA clinical trials: state of the art With the emergence of siRNA-based nanomedicine as a powerful therapeutic strategy for…
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2012
2012
The interaction of PKN3 with RhoC promotes malignant growth
K. Unsal-Kaçmaz
,
S. Ragunathan
,
+6 authors
A. Klippel
Molecular Oncology
2012
Corpus ID: 44725353
2011
2011
Site recognition and substrate screens for PKN family proteins.
Alejandra Collazos
,
N. Michael
,
+5 authors
P. Parker
Biochemical Journal
2011
Corpus ID: 1891057
The PRKs [protein kinase C-related kinases; also referred to as PKNs (protein kinase Ns)] are a kinase family important in…
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Highly Cited
2010
Highly Cited
2010
Atu027 Prevents Pulmonary Metastasis in Experimental and Spontaneous Mouse Metastasis Models
A. Santel
,
M. Aleku
,
+15 authors
J. Kaufmann
Clinical Cancer Research
2010
Corpus ID: 207695371
Purpose: Atu027, a novel RNA interference therapeutic, has been shown to inhibit lymph node metastasis in orthotopic prostate…
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Highly Cited
2004
Highly Cited
2004
PKN3 is required for malignant prostate cell growth downstream of activated PI 3‐kinase
F. Leenders
,
Kristin Moepert
,
+12 authors
A. Klippel
EMBO Journal
2004
Corpus ID: 33515415
Chronic activation of the phosphoinositide 3‐kinase (PI3K)/PTEN signal transduction pathway contributes to metastatic cell growth…
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2001
2001
PKNbeta interacts with the SH3 domains of Graf and a novel Graf related protein, Graf2, which are GTPase activating proteins for Rho family.
H. Shibata
,
K. Oishi
,
A. Yamagiwa
,
M. Matsumoto
,
H. Mukai
,
Y. Ono
Journal of Biochemistry (Tokyo)
2001
Corpus ID: 38300650
PKNbeta is a novel isoform of PKNalpha, which is one of the target protein kinases for the small GTPase Rho. By yeast two-hybrid…
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2001
2001
PKN Regulates Phospholipase D1 through Direct Interaction*
K. Oishi
,
M. Takahashi
,
+5 authors
Y. Ono
Journal of Biological Chemistry
2001
Corpus ID: 6093487
The association of phospholipase (PLD)-1 with protein kinase C-related protein kinases, PKNα and PKNβ, was analyzed. PLD1…
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1999
1999
Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.
K. Oishi
,
H. Mukai
,
H. Shibata
,
M. Takahashi
,
Y. Ona
Biochemical and Biophysical Research…
1999
Corpus ID: 26659398
The cDNA clone encoding a novel isoform of protein kinase PKN, termed PKNbeta, was isolated from a HeLa cDNA library. PKNbeta had…
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