PKN3 gene

Known as: PROTEIN KINASE N3, PKN3, PKNbeta 
 
National Institutes of Health

Related topics

Related topics

1 relation
protein kinase Nbeta

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The interaction of p130Cas with PKN3 promotes malignant growth
Protein p130Cas constitutes an adaptor protein mainly involved in integrin signaling downstream of Src kinase. Owing to its… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2016
2016
PKN3 is the major regulator of angiogenesis and tumor metastasis in mice
PKN, a conserved family member related to PKC, was the first protein kinase identified as a target of the small GTPase Rho. PKN… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2012
2012
The interaction of PKN3 with RhoC promotes malignant growth.
PKN3 is an AGC-family protein kinase implicated in growth of metastatic prostate cancer cells with phosphoinositide 3-kinase… (More)
Is this relevant?
2011
2011
Site recognition and substrate screens for PKN family proteins.
The PRKs [protein kinase C-related kinases; also referred to as PKNs (protein kinase Ns)] are a kinase family important in… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
Is this relevant?
2010
2010
Atu027 prevents pulmonary metastasis in experimental and spontaneous mouse metastasis models.
PURPOSE Atu027, a novel RNA interference therapeutic, has been shown to inhibit lymph node metastasis in orthotopic prostate… (More)
  • figure 2
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
2004
2004
PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.
Chronic activation of the phosphoinositide 3-kinase (PI3K)/PTEN signal transduction pathway contributes to metastatic cell growth… (More)
Is this relevant?
2001
2001
PKNbeta interacts with the SH3 domains of Graf and a novel Graf related protein, Graf2, which are GTPase activating proteins for Rho family.
PKNbeta is a novel isoform of PKNalpha, which is one of the target protein kinases for the small GTPase Rho. By yeast two-hybrid… (More)
Is this relevant?
2001
2001
PKN regulates phospholipase D1 through direct interaction.
The association of phospholipase (PLD)-1 with protein kinase C-related protein kinases, PKNalpha and PKNbeta, was analyzed. PLD1… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2000
2000
Pharbitis class-1 knotted-like homeobox gene, PKn3, shares similar characteristics to those of class-2 knotted-like genes
Three novel homeobox genes, PKn1–3 (Pharbitis knotted-like), were isolated from Japanese morning glory (Pharbitis nil Chois… (More)
Is this relevant?
1999
1999
Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.
The cDNA clone encoding a novel isoform of protein kinase PKN, termed PKNbeta, was isolated from a HeLa cDNA library. PKNbeta had… (More)
Is this relevant?