PKN3 gene

Despite recent clinical successes for irreversible drugs, potential toxicities mediated by unpredictable modification of off… Expand

siRNA clinical trials: state of the art With the emergence of siRNA-based nanomedicine as a powerful therapeutic strategy for… Expand

PKN3 is an AGC‐family protein kinase implicated in growth of metastatic prostate cancer cells with phosphoinositide 3‐kinase… Expand

The PRKs [protein kinase C-related kinases; also referred to as PKNs (protein kinase Ns)] are a kinase family important in… Expand

Purpose: Atu027, a novel RNA interference therapeutic, has been shown to inhibit lymph node metastasis in orthotopic prostate… Expand

Chronic activation of the phosphoinositide 3‐kinase (PI3K)/PTEN signal transduction pathway contributes to metastatic cell growth… Expand

The association of phospholipase (PLD)-1 with protein kinase C-related protein kinases, PKNα and PKNβ, was analyzed. PLD1… Expand

PKNbeta is a novel isoform of PKNalpha, which is one of the target protein kinases for the small GTPase Rho. By yeast two-hybrid… Expand

Abstract Three novel homeobox genes, PKn1–3 (Pharbitis knotted-like), were isolated from Japanese morning glory (Pharbitis nil… Expand

The cDNA clone encoding a novel isoform of protein kinase PKN, termed PKNbeta, was isolated from a HeLa cDNA library. PKNbeta had… Expand