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PKMYT1 gene

Known as: MYT1, CDC2-INHIBITORY KINASE, MEMBRANE-ASSOCIATED TYROSINE/THREONINE, 1, PPP1R126 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
BLM germline and somatic PKMYT1 and AHCY mutations: Genetic variations beyond MYCN and prognosis in neuroblastoma.
2016
2016
Abstract 4370: Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in patient-derived glioblastoma stem-like cells
Glioblastoma multiforme (GBM) is the most aggressive and common form of brain cancer in adults. There are currently no effective… 
2016
2016
PKMYT1 no longer has to play second fiddle to WEE1
2015
2015
The glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6′-amino-6′-deoxy-α-d-glucosyl)-sn-glycerol is no inhibitor of the human Myt1 kinase
Abstract Previously, a glycoglycerolipid isolated from marine algae was reported to be a potent and selective inhibitor of the… 
2013
2013
Small Molecule Therapeutics Preclinical Evaluation of the WEE 1 Inhibitor MK-1775 as Single-Agent Anticancer Therapy
Inhibitionof theDNAdamage checkpoint kinaseWEE1potentiates genotoxic chemotherapies byabrogating cell-cycle arrest and proper DNA… 
2013
2013
Compositions and methods for treatment of malignant tumour
FIELD: medicine. SUBSTANCE: group of inventions relates to medicine and can be used to treat a patient with a malignant tumour… 
2013
2013
Differential DNA Methylation Predicts Response To Combined Treatment Regimens With a DNA Methyltransferase Inhibitor In Acute Myeloid Leukemia (AML)
Deregulated epigenetic mechanisms have been identified as major components of acute myeloid leukemia (AML) pathogenesis. This… 
2012
2012
In vitro and in silico studies on substrate recognition and acceptance of human PKMYT1, a Cdk1 inhibitory kinase.
2011
2011
A critical balance between Cyclin B synthesis and Myt1 activity controls meiosis entry in Xenopus oocytes
In fully grown oocytes, meiosis is arrested at first prophase until species-specific initiation signals trigger maturation… 
2006
2006
Mechanistic studies of the inhibition of Myt1 kinase after fertilization of Xenopus eggs
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