Skip to search formSkip to main contentSkip to account menu

PINK1 gene

Known as: PINK1, PTEN induced putative kinase 1, PTEN-INDUCED PUTATIVE KINASE 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Destructive cellular paths underlying familial and sporadic Parkinson disease converge on mitophagy
ABSTRACT The knowledge gap separating the molecular and cellular underpinnings of Parkinson disease (PD) and its pathology… 
2016
2016
Atp13a2 expression in the periaqueductal gray is decreased in the Pink1 -/- rat model of Parkinson disease
2016
2016
Constitutive Activation of PINK1 Protein Leads to Proteasome-mediated and Non-apoptotic Cell Death Independently of Mitochondrial Autophagy*
Phosphatase and tensin homolog-induced putative kinase 1 (PINK1), a Ser/Thr kinase, and PARKIN, a ubiquitin ligase, are causal… 
Review
2015
Review
2015
PINK1 activation-turning on a promiscuous kinase.
PINK1 [phosphatase and tensin homologue (PTEN)-induced putative kinase 1] is a serine/threonine kinase targeted to mitochondria… 
2015
2015
PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation
Parkinson's disease (PD) is characterized by progressive dopaminergic neuronal loss and the formation of abnormal protein… 
2012
2012
PINK1 stimulates interleukin-1β-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1
Parkinson’s disease (PD) is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. The cause of… 
Highly Cited
2010
Highly Cited
2010
PINK1/Parkin direct mitochondria to autophagy
Mutations in PTEN-induced putative kinase 1 (PINK1) and PARK2/Parkin cause autosomal recessive forms of Parkinson disease. In… 
2010
2010
Existence of Pink1 Antisense RNAs in Mouse and Their Localization
PTEN-induced kinase 1 (PINK1), which is identified as the gene transactivated by the tumor suppressor PTEN, has been found to be… 
2008
2008
PINK1 in mitochondrial function
Rare, inherited mutations causing familial forms of Parkinson's disease (PD) have provided much insight into some of the… 
2008
2008
Mitochondrial PINK1—A Novel Cardioprotective Kinase?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)