Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

PIK3CA NP_006209.2:p.H1047X

Known as: PIK3CA H1047 Mutation, PI3Kalpha H1047X, PIK3CA p.His1047Xxx 
A change in the amino acid residue at position 1047 in the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform protein… Expand
National Institutes of Health

Related topics

Related topics

1 relation
PIK3CA Gene Mutation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Putative functional variants of PI3K/AKT/mTOR pathway are associated with knee osteoarthritis susceptibility
Osteoarthritis (OA) is a degenerative musculoskeletal disease which causes joint deformity and pain and finally leads to limb… Expand
Is this relevant?
2019
2019
Einsatz von Alpelisib beim fortgeschrittenen PIK3CA-mutierten Mammakarzinom
André F, Ciruelos E, Rubovszky G, Campone M, Loibl S, Rugo HS, Iwata H, Conte P, Mayer IA, Kaufman B, Yamashita T, Lu YS, Inoue K… Expand
Is this relevant?
2019
2019
Mutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing.
Background: Ependymomas are glial tumors derived from differentiated ependymal cells. In contrast to other types of brain tumors… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2018
2018
Unexpected Benefit from Alpelisib and Fulvestrant in a Woman with Highly Pre-treated ER-Positive, HER2-Negative PIK3CA Mutant Metastatic Breast Cancer
We present the case of a postmenopausal patient with a secondary metastatic ER-positive, HER2-negative breast cancer who was… Expand
  • figure 1
  • figure 2
Is this relevant?
2017
2017
Inhibitors of STAT3, β‐catenin, and IGF‐1R sensitize mouse PIK3CA‐mutant breast cancer to PI3K inhibitors
Although mutations in the phosphoinositide 3‐kinase catalytic subunit (PIK3CA) are common in breast cancer, PI3K inhibitors alone… Expand
Is this relevant?
2014
2014
Prognostic and predictive value of p-Akt, EGFR, and p-mTOR in early breast cancer
Background and purposeThere are scarce data available on the prognostic/predictive value of p-Akt and p-mTOR protein expression… Expand
  • figure 1 8
  • figure 2 8
  • table 2
  • table 1
  • figure 3 8
Is this relevant?
2013
2013
Phosphatidylinositol-3-Kinase p110d Uniquely Promotes Gain-Of-Function PTPN11-Induced GM-CSF Hypersensitivity In a Model Of Juvenile Myelomonocytic Leukemia
Juvenile myelomonocytic leukemia (JMML) is a fatal leukemia affecting children under the age of 4 years and is characterized by… Expand
Is this relevant?
2012
2012
A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P2
All Kv7 potassium channels require membrane phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2) for their normal function and hence… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2010
2010
Multiple onkogene Mutationen in seborrhoischen Keratosen
Onkogene Mutationen gehören zu den klassischen „hallmarks of cancer“ [1]. Sie betreffen häufig Rezeptoren oder Signalmoleküle… Expand
Is this relevant?
2008
2008
PIK3CA Mutationen bei Patienten mit hepatozellulärem Karzinom eines deutschen Kollektivs
 
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE