PIK3CA NP_006209.2:p.H1047R

Known as: Phosphoinositide-3-Kinase Catalytic Alpha Polypeptide H1047R, PIK3CA p.Glu1047Arg, Phosphatidylinositol-4,5-Bisphosphate 3-Kinase 110 kDa Catalytic Subunit Alpha H1047R 
A change in the amino acid residue at position 1047 in the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2018
012319972018

Papers overview

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2016
2016
Mutant cancer subpopulations have the potential to derail durable patient responses to molecularly targeted cancer therapeutics… (More)
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2016
2016
Phosphatidylinositol 3-kinase (PI3K)/AKT pathway aberrations are common in human breast cancer. Furthermore, PIK3CA mutations are… (More)
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2016
2016
The PIK3CA H1047R mutation is considered to be a potential predictive biomarker for EGFR-targeted therapies. In this study, we… (More)
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2014
2014
Solid-supported lipid bilayers (SLBs) mimicking a biological membrane are commonly used to investigate lipid-lipid or lipid… (More)
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Highly Cited
2011
Highly Cited
2011
CONTEXT The phosphoinositide 3-kinase (PI3K)/Akt pathway is widely postulated to be an effective therapeutic target in thyroid… (More)
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Highly Cited
2011
Highly Cited
2011
The phosphoinositide 3-kinase (PI3K) signaling cascade, a key mediator of cellular survival, growth, and metabolism, is… (More)
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2010
2010
The phosphatidylinositol-3-kinase (PI3K)-protein kinase B (Akt)-mammalian target of rapamycin (mTOR) signaling pathway is often… (More)
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Highly Cited
2008
Highly Cited
2008
Somatic mutations that activate phosphoinositide 3-kinase (PI3K) have been identified in the p110-α catalytic subunit (encoded by… (More)
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2005
2005
Presynaptic inhibition of transmitter release is commonly mediated by a direct interaction between G protein betagamma subunits… (More)
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Highly Cited
1997
Highly Cited
1997
Phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2), a key molecule in the phosphoinositide signalling pathway, was thought to… (More)
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