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PIK3CA NP_006209.2:p.H1047R

Known as: Phosphoinositide-3-Kinase Catalytic Alpha Polypeptide H1047R, PIK3CA p.Glu1047Arg, Phosphatidylinositol-4,5-Bisphosphate 3-Kinase 110 kDa Catalytic Subunit Alpha H1047R 
A change in the amino acid residue at position 1047 in the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform protein… Expand
National Institutes of Health

Papers overview

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2020
2020
Purpose PIK3CA, encoding for subunit p110a of PI3K, is frequently mutated in breast cancer. PIK3CA mutation was predictive for… Expand
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2020
2020
Dear Editor, While in Burkitt lymphoma (BL) immunochemotherapy readily induces remissions, the clinical outcomes for patients… Expand
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2018
2018
There is currently no blood-based marker in routine use for endometrial cancer patients. Such a marker could potentially be used… Expand
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2018
2018
Background: Blood analytes, as liquid biopsies, are discussed to be surrogate markers for therapy stratification, as serial… Expand
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2016
2016
Mutant cancer subpopulations have the potential to derail durable patient responses to molecularly targeted cancer therapeutics… Expand
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2016
2016
PurposePhosphatidylinositol 3-kinase (PI3K)/AKT pathway aberrations are common in human breast cancer. Furthermore, PIK3CA… Expand
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2016
2016
BackgroundThe PIK3CAH1047R mutation is considered to be a potential predictive biomarker for EGFR-targeted therapies. In this… Expand
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2015
2015
The signaling network of phosphatidylinositol 3-kinase (PI3K) and Akt controls cell cycle, survival, metabolism and genomic… Expand
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2015
2015
Little is known about the role of low-frequency somatic mutations in breast cancer, a cancer that is quite variable in terms of… Expand
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2011
2011
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL Background: Circulating free DNA (cfDNA) represents a… Expand
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