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, Phosphoinositide-3-Kinase Catalytic Alpha Polypeptide E545K
, PI3Kalpha E545K
A change in the amino acid residue at position 545 in the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform protein…
National Institutes of Health
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Biomarkers of Response to Akt Inhibitor MK-2206 in Breast Cancer
Clinical Cancer Research
Corpus ID: 510965
Purpose: We tested the hypothesis that allosteric Akt inhibitor MK-2206 inhibits tumor growth, and that PTEN/PIK3CA mutations…
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