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PI3Kdelta Inhibitor INCB040093
Known as:
INCB040093
An orally bioavailable, selective inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinases (PI3K) with…
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National Institutes of Health
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2015
2015
Interim analysis of a phase I study of INCB040093, a PI3Kδ inhibitor, alone or in combination with INCB039110, a selective JAK1 inhibitor, in patients (pts) with relapsed or refractory (r/r) B-cell…
T. Phillips
,
A. Forero-Torres
,
+9 authors
P. Barr
2015
Corpus ID: 78728847
8520 Background: Inhibiting the PI3K or JAK-STAT pathways may be therapeutic in B-cell malignancies due to their contribution to…
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2015
2015
A phase 2 trial of INCB040093 alone or in combination with INCB039110 in patients (pts) with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL).
P. Barr
,
T. Sher
,
+5 authors
A. Forero-Torres
2015
Corpus ID: 79425373
TPS8607 Background: In vitro data suggest that both the PI3K and JAK-STAT pathways contribute to tumor growth and survival in HL…
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