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PHF6 gene

Known as: centromere protein 31, PHD finger protein 6, CENP-31 
This gene plays a role in transcriptional regulation.
National Institutes of Health

Related topics

Related topics

2 relations
PHF5A geneTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The misfolding mechanism of the key fragment R3 of tau protein: a combined molecular dynamics simulation and Markov state model study.
The formation of neurofibrillary tangles (NFT) by abnormal aggregation of misfolded microtubule-associated protein tau is a… 
2019
2019
Tryptophan-glucosamine conjugates modulate tau-derived PHF6 aggregation at low concentrations.
Glycosylation of amyloidogenic proteins enhances their solubility and reduces propensity for aggregation. We therefore, prepared… 
2016
2016
Naphthoquinone-Tryptophan Hybrid Inhibits Aggregation of the Tau-Derived Peptide PHF6 and Reduces Neurotoxicity.
Tauopathies, such as Alzheimer's disease (AD), are a group of disorders characterized neuropathologically by intracellular toxic… 
2016
2016
Co-existence of PHF6 and NOTCH1 mutations in adult T-cell acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia (T-ALL) results from the collaboration of multiple genetic abnormalities in the… 
2014
2014
Alternative Conformations of the Tau Repeat Domain in Complex with an Engineered Binding Protein*
Background: Aggregates of the protein Tau are associated with Alzheimer disease and other neurodegenerative diseases. Results… 
2012
2012
Positional effects of phosphorylation on the stability and morphology of tau-related amyloid fibrils.
Hyperphosphorylated forms of tau protein are the main component of paired helical filaments (PHFs) of neurofibrillary tangles in… 
2008
2008
Charge-pairing mechanism of phosphorylation effect upon amyloid fibrillation of human tau core peptide.
Phosphorylation of a fibrillogenic protein, human tau, is believed to play crucial roles in the pathogenesis of Alzheimer's… 
2007
2007
Novel conformation-sensitive antibodies specific to three- and four-repeat tau.
2004
2004
Clinical and behavioral features of patients with Borjeson-Forssman-Lehmann syndrome with mutations in PHF6.
Review
2004
Review
2004
A novel PHF6 mutation results in enhanced exon skipping and mild Börjeson-Forssman-Lehmann syndrome
BFLS is a rare X linked recessive disorder characterised by moderate to severe mental retardation, obesity with gynaecomastia… 
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