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PHA 543,613

Known as: PHA-543613, PHA543613, PHA-543,613 
National Institutes of Health

Papers overview

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2019
2019
Cognitive Enhancer Effects of Low Memantine Doses Are Facilitated by an Alpha7 Nicotinic Acetylcholine Receptor Agonist in Scopolamine-Induced Amnesia in Rats
Alpha7 nicotinic acetylcholine receptors (nAChRs) play an important role in learning and memory and are promising targets for… 
2018
2018
Additive counteraction by &agr;7 and &agr;4&bgr;2‐nAChRs of the hypotension and cardiac sympathovagal imbalance evoked by endotoxemia in male rats
Highly Cited
2015
Highly Cited
2015
Selective activation of α7 nicotinic acetylcholine receptor by PHA-543613 improves Aβ25–35-mediated cognitive deficits in mice
2015
2015
Effect of alpha-7 nicotinic acetylcholine receptor activation on beta-amyloid induced recognition memory impairment. Possible role of neurovascular function.
PURPOSE To evaluate the effects of PHA-543613 (α7-nAChR agonist) and galantamine (acetylcholinesterase inhibitor (AChEI)) on… 
2015
2015
Assessment of the Protection of Dopaminergic Neurons by an α7 Nicotinic Receptor Agonist, PHA 543613 Using [18F]LBT-999 in a Parkinson’s Disease Rat Model
The inverse association between nicotine intake and Parkinson’s disease (PD) is well established and suggests that this molecule… 
2015
2015
Activation of spinal alpha-7 nicotinic acetylcholine receptor attenuates remifentanil-induced postoperative hyperalgesia.
The activation of alpha-7 nicotinic acetylcholine receptors (α7-nAchRs) are currently being considered as novel therapeutic… 
Highly Cited
2013
Highly Cited
2013
Effects of alpha 7 positive allosteric modulators in murine inflammatory and chronic neuropathic pain models
2013
2013
The Role of α7 Nicotinic Acetylcholine Receptor in Modulation of Heart Rate Dynamics in Endotoxemic Rats
Previous reports have indicated that artificial stimulation of the vagus nerve reduces systemic inflammation in experimental… 
2012
2012
Beta Amyloid Differently Modulate Nicotinic and Muscarinic Receptor Subtypes which Stimulate in vitro and in vivo the Release of Glycine in the Rat Hippocampus
Using both in vitro (hippocampal synaptosomes in superfusion) and in vivo (microdialysis) approaches we investigated whether and… 
2012
2012
Galantamine increases hippocampal insulin-like growth factor 2 expression via α7 nicotinic acetylcholine receptors in mice
Galantamine, a drug for the treatment of Alzheimer’s disease, has neuroprotection in several experimental models and stimulates… 
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