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PFKFB1 gene

Known as: PFKFB, LIVER, PFKFB1, 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 1 
 
National Institutes of Health

Papers overview

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2017
2017
Although mTOR (mammalian target of rapamycin) activation is frequently observed in acute myeloid leukemia (AML) patients, the… Expand
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Highly Cited
2014
Highly Cited
2014
The control of glucose metabolism and the cell cycle must be coordinated in order to guarantee sufficient ATP and anabolic… Expand
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2013
2013
The bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) catalyzes the synthesis and… Expand
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2010
2010
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Osteosarcoma (OS) is the most common malignant… Expand
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2009
2009
AIMS Fructose-2,6-bisphosphate, a key regulator of glycolysis, is synthesized and degraded by four different isozymes of 6… Expand
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2006
2006
Aims/hypothesisGlucokinase (GCK) acts as a glucose sensor in the pancreatic beta cell and regulates insulin secretion. In the… Expand
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Review
2006
Review
2006
  • Martin Flück
  • Journal of Experimental Biology
  • 2006
  • Corpus ID: 7210868
SUMMARY Biological systems have acquired effective adaptive strategies to cope with physiological challenges and to maximize… Expand
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2006
2006
The hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) plays a crucial role in the… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: Fructose 2,6-bisphosphate (F2,6BP) is a potent activator of phosphofructokinase, which is a rate-limiting enzyme of… Expand
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1997
1997
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) catalyzes the synthesis and degradation of fructose-2,6… Expand
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