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PFKFB1 gene

Known as: PFKFB, LIVER, PFKFB1, 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 1 
 
National Institutes of Health

Papers overview

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2017
2017
Although mTOR (mammalian target of rapamycin) activation is frequently observed in acute myeloid leukemia (AML) patients, the… Expand
Highly Cited
2014
Highly Cited
2014
The control of glucose metabolism and the cell cycle must be coordinated in order to guarantee sufficient ATP and anabolic… Expand
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2013
2013
The bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) catalyzes the synthesis and… Expand
2010
2010
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Osteosarcoma (OS) is the most common malignant… Expand
2009
2009
Aims: Fructose‐2,6‐bisphosphate, a key regulator of glycolysis, is synthesized and degraded by four different isozymes of 6… Expand
Highly Cited
2006
Highly Cited
2006
Aims/hypothesisGlucokinase (GCK) acts as a glucose sensor in the pancreatic beta cell and regulates insulin secretion. In the… Expand
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Review
2006
Review
2006
  • M. Flück
  • Journal of Experimental Biology
  • 2006
  • Corpus ID: 7210868
SUMMARY Biological systems have acquired effective adaptive strategies to cope with physiological challenges and to maximize… Expand
2006
2006
The hypoxia-inducible form of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) plays a crucial role in the… Expand
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Highly Cited
2005
Highly Cited
2005
Purpose: Fructose 2,6-bisphosphate (F2,6BP) is a potent activator of phosphofructokinase, which is a rate-limiting enzyme of… Expand
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1997
1997
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) catalyzes the synthesis and degradation of fructose-2,6… Expand