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PF-5190457

National Institutes of Health

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3 relations

Broader (2)

AzetidinesSpiro Compounds

Narrower (1)

PF-05190457

Papers overview

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2019
2019
Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach
(R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7… 
2019
2019
Development and validation of an assay for a novel ghrelin receptor inverse agonist PF-5190457 and its major hydroxy metabolite (PF-6870961) by LC-MS/MS in human plasma.
2017
2017
Biotransformation and Pharmacokinetic Evaluation of PF-5190457, A Novel Drug Candidate for Alcoholism
Alcohol use disorder is a chronic condition characterized by an inability to control alcohol intake. Recent research has shown… 
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