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PF 4455242

Known as: PF-4455242, PF4455242 
National Institutes of Health

Papers overview

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2013
2013
Insight into the binding model of new antagonists of kappa receptor using docking and molecular dynamics simulation
PF-4455242 and its analogues represent a new series of kappa opioid selective antagonists that demonstrate high selectivity and… 
2011
2011
Design and discovery of a selective small molecule κ opioid antagonist (2-methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine, PF-4455242).
By use of parallel chemistry coupled with physicochemical property design, a series of selective κ opioid antagonists have been… 
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