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PF-04554878

National Institutes of Health

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defactinib

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2012
2012
567 A Novel Focal Adhesion Kinase Inhibitor (PF-04554878) Decreases Growth and Induces Apoptosis in Pancreatic Neuroendocrine Tumor Cells
2011
2011
Phase I study of PF-04554878, a second-generation focal adhesion kinase (FAK) inhibitor, in patients with advanced solid tumors.
3002 Background: FAK is a non-receptor tyrosine kinase that transduces signaling from integrins and growth factor receptors to… 
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