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PEX16 gene
Known as:
PEX16
, peroxisomal biogenesis factor 16
, PEROXISOME BIOGENESIS FACTOR 16
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission
Hongsuk Park
,
Anyuan He
,
+9 authors
I. Lodhi
The Journal of clinical investigation
2019
Corpus ID: 54569273
Peroxisomes perform essential functions in lipid metabolism, including fatty acid oxidation and plasmalogen synthesis. Here, we…
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Highly Cited
2017
Highly Cited
2017
Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes
Ayumu Sugiura
,
S. Mattie
,
J. Prudent
,
H. McBride
Nature
2017
Corpus ID: 4460814
Peroxisomes function together with mitochondria in a number of essential biochemical pathways, from bile acid synthesis to fatty…
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Highly Cited
2011
Highly Cited
2011
Sec16B is involved in the endoplasmic reticulum export of the peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in mammalian cells
S. Yonekawa
,
A. Furuno
,
+5 authors
K. Tani
Proceedings of the National Academy of Sciences
2011
Corpus ID: 1431553
Sec16 plays a key role in the formation of coat protein II vesicles, which mediate protein transport from the endoplasmic…
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Highly Cited
2010
Highly Cited
2010
Identification of an unusual variant peroxisome biogenesis disorder caused by mutations in the PEX16 gene
M. S. Ebberink
,
B. Csányi
,
+12 authors
S. Ferdinandusse
Journal of Medical Genetics
2010
Corpus ID: 4616525
Background Zellweger syndrome spectrum disorders are caused by mutations in any of at least 12 different PEX genes. This includes…
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Review
2009
Review
2009
How peroxisomes multiply
E. Hettema
,
A. Motley
Journal of Cell Science
2009
Corpus ID: 13908372
With every cell division, peroxisomes duplicate and are segregated between progeny cells. Here, we discuss the different modes of…
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Highly Cited
2006
Highly Cited
2006
The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER
P. Kim
,
R. Mullen
,
U. Schumann
,
J. Lippincott-Schwartz
The Journal of cell biology
2006
Corpus ID: 17505443
Peroxisomes are ubiquitous organelles that proliferate under different physiological conditions and can form de novo in cells…
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Highly Cited
2002
Highly Cited
2002
The Membrane Biogenesis Peroxin Pex16p
M. Honsho
,
Takanobu Hiroshige
,
Y. Fujiki
The Journal of Biological Chemistry
2002
Corpus ID: 30279969
Previously we isolated human PEX16encoding 336-amino acid-long peroxin Pex16p and showed that its dysfunction was responsible for…
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Highly Cited
1999
Highly Cited
1999
Peroxisome Synthesis in the Absence of Preexisting Peroxisomes
S. South
,
S. Gould
The Journal of cell biology
1999
Corpus ID: 9261817
Zellweger syndrome and related diseases are caused by defective import of peroxisomal matrix proteins. In all previously reported…
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Highly Cited
1998
Highly Cited
1998
Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.
M. Honsho
,
S. Tamura
,
N. Shimozawa
,
Y. Suzuki
,
N. Kondo
,
Y. Fujiki
American journal of human genetics
1998
Corpus ID: 29380246
Peroxisome-biogenesis disorders (PBDs), including Zellweger syndrome (ZS), are autosomal recessive diseases caused by a…
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Highly Cited
1997
Highly Cited
1997
Enlarged Peroxisomes Are Present in Oleic Acid–grown Yarrowia lipolytica Overexpressing the PEX16 Gene Encoding an Intraperoxisomal Peripheral Membrane Peroxin
G. Eitzen
,
R. Szilard
,
R. Rachubinski
The Journal of cell biology
1997
Corpus ID: 16717745
Pex mutants of the yeast Yarrowia lipolytica are defective in peroxisome assembly. The mutant strain pex16-1 lacks…
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