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PELI1 gene

Known as: PELI1, PELLINO, DROSOPHILA, HOMOLOG OF, 1, pellino E3 ubiquitin protein ligase 1 
 
National Institutes of Health

Papers overview

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2018
2018
Systemic lupus erythematosus (SLE) is characterized by uncontrolled secretion of autoantibodies by plasma cells. Although the… Expand
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2018
2018
Though experimental, stem cell transplantation has the potential to improve the condition of the heart after myocardial… Expand
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2017
2017
Early brain injury (EBI) following subarachnoid hemorrhage (SAH) is closely associated with neuroinflammation. Microglial… Expand
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2016
2016
PELI is a family of E3 ubiquitin ligases that regulate protein activity through a post-translational modification, ubiquitination… Expand
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Highly Cited
2013
Highly Cited
2013
Microglia are crucial for the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis… Expand
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2013
2013
The RAS-RAF-MEK-ERK signaling kinase pathway has been the focus of intense cancer drug development efforts because of its central… Expand
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Highly Cited
2011
Highly Cited
2011
T cell activation is subject to tight regulation to avoid inappropriate responses to self antigens. Here we show that genetic… Expand
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2011
2011
T cell tolerance is essential to the prevention of autoimmunity. The ubiquitin E3 ligase Peli1 acts as a negative regulator of T… Expand
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Highly Cited
2010
Highly Cited
2010
During liver regeneration, normally quiescent liver cells reenter the cell cycle, nonparenchymal and parenchymal cells divide… Expand
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Highly Cited
2009
Highly Cited
2009
Toll-like receptors (TLRs) are pivotal in innate immunity and inflammation. Here we show that genetic deficiency in Peli1, an E3… Expand
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