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PDXP gene

Known as: CHRONOPHIN, dJ37E16.5, PLP PHOSPHATASE 
National Institutes of Health

Related topics

Related topics

1 relation
22q

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Cofilin, a Master Node Regulating Cytoskeletal Pathogenesis in Alzheimer’s Disease
The defining pathological hallmarks of Alzheimer’s disease (AD) are proteinopathies marked by the amyloid-β (Aβ) peptide and… 
Review
2013
Review
2013
Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation.
2013
2013
Evolutionary and Structural Analyses of Mammalian Haloacid Dehalogenase-type Phosphatases AUM and Chronophin Provide Insight into the Basis of Their Different Substrate Specificities*
Background: Substrate specificity determinants of mammalian haloacid dehalogenase (HAD) phosphatases are poorly understood… 
Highly Cited
2010
Highly Cited
2010
ALDH1L1 Inhibits Cell Motility Via Dephosphorylation of Cofilin by PP1 and PP2A
Here we report that ALDH1L1 (FDH, a folate enzyme with tumor suppressor-like properties) inhibits cell motility. The underlying… 
Highly Cited
2008
Highly Cited
2008
Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation.
Highly Cited
2007
Highly Cited
2007
The Slingshot Family of Phosphatases Mediates Rac1 Regulation of Cofilin Phosphorylation, Laminin-332 Organization, and Motility Behavior of Keratinocytes*
The motility of keratinocytes is an essential component of wound closure and the development of epidermal tumors. In vitro, the… 
2007
2007
Beta‐arrestin‐dependent regulation of the cofilin pathway downstream of Protease‐activated receptor‐2
β‐arrestins are pleiotropic molecules that mediate signal desensitization, G‐protein‐independent signaling, scaffolding of… 
Review
2006
Review
2006
Cofilin phosphatases and regulation of actin dynamics.
Highly Cited
2005
Highly Cited
2005
Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics
Cofilin is a key regulator of actin cytoskeletal dynamics whose activity is controlled by phosphorylation of a single serine… 
1955
1955
FURTHER EVIDENCE OF ABERRANT RECOMBINATION IN Neurospora.
Wild progeny from intercrosses of pyridoxine mutants have been found in tetrads showing irregular segregation of one or the other… 
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