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PDK1 wt Allele

Known as: PDHK1, Pyruvate Dehydrogenase Kinase, Isozyme 1 wt Allele 
Human PDK1 wild-type allele is located in the vicinity of 2q31.1 and is approximately 70 kb in length. This allele, which encodes [pyruvate… 
National Institutes of Health

Related topics

Related topics

10 relations
2q31.1B Cell Receptor Signaling PathwayCarbohydrate MetabolismMast/Stem Cell Growth Factor Receptor Signaling Pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Early TCR Signaling Sweetens Effector Function through PDHK1
2018
2018
Abstract 2435: ST6Gal-I sialylation potentiates hypoxia adaptation by enhancing HIF-1a signaling
Aberrant surface glycosylation is a well-known hallmark of a tumor cell, however the functional role of glycans in cancer cell… 
2018
2018
Faculty of 1000 evaluation for Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.
2016
2016
Novel Approach Synthesis, Molecular Docking and Cytotoxic Activity Evaluation of N-phenyl-2,2- dichloroacetamide Derivatives as Anticancer Agents
Dichloroacetate (DCA) as a small, cheap and available anticancer agent, is a pyruvate mimetic compound that stimulates the… 
2016
2016
Explorer A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models
  • 2016
  • Corpus ID: 264704413
Many cancer cells rely on aerobic glycolysis for energy production and targeting of this pathway is a potential strategy to… 
2016
2016
Abstract 2797: Role of the ST6Gal-I glycosyltransferase in protecting tumor cells against hypoxia
A change in surface glycosylation was one of the first identified hallmarks of a cancer cell, however an understanding of how… 
2015
2015
Metabolic signatures of renal cell carcinoma.
2015
2015
Pyruvate dehydrogenase kinase 1 (PDHK1) regulates ovarian cancer cell migration, invasion, and chemoresistance and contributes to poor prognosis in patients
Conference Theme: Anticancer Drug Action and Drug Resistance: From Cancer Biology to the Clinic 
2015
2015
Role of pyruvate dehydrogenase kinase 1 (PDHK1) in tumorigenesis and metastasis of ovarian cancer
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