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PD 166793

Known as: PD-166793, PD166793 
 
National Institutes of Health

Papers overview

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2012
2012
Collagen-I is thought to be the main component of the extracellular matrix in cardiac fibrosis, the accumulation of which occurs… Expand
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Highly Cited
2008
Highly Cited
2008
Osteopontin (OPN) plays an important role in left ventricular (LV) remodeling after myocardial infarction (MI) by promoting… Expand
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Highly Cited
2007
Highly Cited
2007
Matrix metalloproteinase (MMP)-2 mediates myocardial ischemia-reperfusion injury which is characterized by enhanced peroxynitrite… Expand
Highly Cited
2005
Highly Cited
2005
Cytokine and extracellular matrix (ECM) homeostasis are distinct systems that are each dysregulated in heart failure. Here we… Expand
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Highly Cited
2003
Highly Cited
2003
Background—A potential mechanism for left ventricular (LV) remodeling after myocardial infarction (MI) is activation of the… Expand
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2003
2003
BACKGROUND Global and regional shape changes that occur within the left ventricular wall after myocardial infarction have been… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE Pro-inflammatory cytokines depress myocardial contractile function by enhancing peroxynitrite production, yet the… Expand
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Highly Cited
2001
Highly Cited
2001
BackgroundMatrix metalloproteinase (MMP) activation contributes to tissue remodeling in several disease states, and increased MMP… Expand
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Highly Cited
1999
Highly Cited
1999
The development of congestive heart failure (CHF) is associated with left ventricle (LV) dilation and myocardial remodeling. The… Expand
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1999
1999
Matrix metalloproteinases (MMPs) are implicated in diseases such as arthritis and cancer. Among these enzymes, stromelysin-1 can… Expand