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PCF11 gene

Known as: PCF11 cleavage and polyadenylation factor subunit, PCF11, KIAA0824 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
012319972017

Papers overview

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2015
2015
Pcf11 orchestrates transcription termination pathways in yeast.
In Saccharomyces cerevisiae, short noncoding RNA (ncRNA) generated by RNA polymerase II (Pol II) are terminated by the NRD… (More)
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Highly Cited
2010
Highly Cited
2010
Gene-specific RNA polymerase II phosphorylation and the CTD code
Pol II has a unique CTD on its large subunit that comprises heptad repeats (26 in budding yeast, 52 in humans) with a conserved… (More)
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Highly Cited
2009
Highly Cited
2009
Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11.
We investigated recruitment of the yeast mRNA export factor Yra1 to the transcription elongation complex (TEC). Previously, the… (More)
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Highly Cited
2008
Highly Cited
2008
The Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain
RNA polymerase II (Pol II) in Saccharomyces cerevisiae can terminate transcription via several pathways. To study how a mechanism… (More)
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2008
2008
Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination
The poly(A) (pA) signal possesses a dual function in 3' end processing of pre-mRNA and in transcriptional termination of RNA… (More)
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2007
2007
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
Pcf11 and Clp1 are subunits of cleavage factor IA (CFIA), an essential polyadenylation factor in Saccahromyces cerevisiae. We… (More)
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2006
2006
Pcf11 is a termination factor in Drosophila that dismantles the elongation complex by bridging the CTD of RNA polymerase II to the nascent transcript.
The mechanism by which Pol II terminates transcription in metazoans is not understood. We show that Pcf11 is directly involved in… (More)
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2005
2005
CTD-dependent dismantling of the RNA polymerase II elongation complex by the pre-mRNA 3'-end processing factor, Pcf11.
Pcf11 is one of numerous proteins involved in pre-mRNA 3'-end processing and transcription termination. Using elongation… (More)
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Highly Cited
2004
Highly Cited
2004
Recognition of RNA polymerase II carboxy-terminal domain by 3′-RNA-processing factors
During transcription, RNA polymerase (Pol) II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing by… (More)
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1997
1997
PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I.
Cleavage and polyadenylation factor I (CF I) is one of four factors required in vitro for yeast pre-mRNA 3'-end processing. Two… (More)
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