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PCF11 gene

Known as: PCF11 cleavage and polyadenylation factor subunit, PCF11, KIAA0824 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Negative Elongation Factor (NELF) Coordinates RNA Polymerase II Pausing, Premature Termination, and Chromatin Remodeling to Regulate HIV Transcription*
Background: Multiple mechanisms contribute to HIV latency, including NELF-mediated RNA polymerase II (RNAP II) pausing. Results… 
Highly Cited
2012
Highly Cited
2012
CTD Tyrosine Phosphorylation Impairs Termination Factor Recruitment to RNA Polymerase II
Don't Terminate Me! DNA transcription progresses through three phases—initiation, elongation, and termination—of messenger RNA… 
Highly Cited
2010
Highly Cited
2010
Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain
Phosphorylation of the C-terminal domain (CTD) of RNA polymerase II controls the co-transcriptional assembly of RNA processing… 
Highly Cited
2009
Highly Cited
2009
Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11.
Highly Cited
2008
Highly Cited
2008
The Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain
RNA polymerase II (Pol II) in Saccharomyces cerevisiae can terminate transcription via several pathways. To study how a mechanism… 
Highly Cited
2006
Highly Cited
2006
The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo model.
The torpedo model of transcription termination by RNA polymerase II proposes that a 5'-3' RNA exonuclease enters at the poly(A… 
Highly Cited
2006
Highly Cited
2006
Pcf11 is a termination factor in Drosophila that dismantles the elongation complex by bridging the CTD of RNA polymerase II to the nascent transcript.
Highly Cited
2005
Highly Cited
2005
CTD-dependent dismantling of the RNA polymerase II elongation complex by the pre-mRNA 3'-end processing factor, Pcf11.
Pcf11 is one of numerous proteins involved in pre-mRNA 3'-end processing and transcription termination. Using elongation… 
Highly Cited
2004
Highly Cited
2004
Recognition of RNA polymerase II carboxy-terminal domain by 3′-RNA-processing factors
During transcription, RNA polymerase (Pol) II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing by… 
Highly Cited
1997
Highly Cited
1997
PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I
Cleavage and polyadenylation factor I (CF I) is one of four factors required in vitro for yeast pre-mRNA 3'-end processing. Two… 
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