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Acute myeloid leukemia (AML) is a highly heterogenous hematological malignancy and its prognostication depends on the… Expand SCOPE
The increased prevalence of cardiovascular diseases (CVDs) has been hypothesized to be the result of an increased exposure… Expand Prostate cancer is characterized by structural rearrangements, most frequently including translocations between androgen… Expand It is well established that the p53 tumor suppressor plays a crucial role in controlling cell proliferation and apoptosis upon… Expand Perturbations in early life environments, including intrauterine exposure to maternal gestational diabetes (GDM), are… Expand Pantothenate kinase (PanK) phosphorylates pantothenic acid (vitamin B5) and controls the overall rate of coenzyme A (CoA… Expand Toll-like receptors (TLRs) modulate the expression of multiple microRNAs (miRNAs). Here, we report the down-regulation of miR-107… Expand Coenzyme A (CoA) biosynthesis is regulated by the pantothenate kinases (PanK), of which there are four active isoforms. The PanK1… Expand Genome-wide association studies (GWAS) of longitudinal birth cohorts enable joint investigation of environmental and genetic… Expand Pantothenate kinase (PanK) is thought to catalyze the first rate-limiting step in CoA biosynthesis. The full-length cDNA encoding… Expand