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Control of protein synthesis is critical for synaptic plasticity and memory formation. However, the molecular mechanisms linking… Expand Mammalian circadian rhythms are synchronized to the external time by daily resetting of the suprachiasmatic nucleus (SCN) in… Expand Translational control plays a key role in late spermiogenesis. A number of mRNAs encoding proteins required for late… Expand The 3' poly(A) tail present on the majority of mature eukaryotic mRNAs is an important regulator of protein synthesis and mRNA… Expand Translation initiation requires the participation of eukaryotic translation initiation factors (eIFs). The poly(A)-binding… Expand The eukaryotic mRNA 3' poly(A) tail and the 5' cap cooperate to synergistically enhance translation. This interaction is mediated… Expand The C‐terminal domain of poly(A)‐binding protein (PABC) is a peptide‐binding domain found in poly(A)‐binding proteins (PABPs) and… Expand The poly(A) tail at the 3' end of mRNAs enhances 5' cap-dependent translation initiation. We show that it also enhances IRES… Expand ABSTRACT The 3′ poly(A) tail of eukaryotic mRNAs and the poly(A) binding protein (PABP) play important roles in the regulation of… Expand ABSTRACT The cap structure and the poly(A) tail of eukaryotic mRNAs act synergistically to enhance translation. This effect is… Expand