Skip to search formSkip to main contentSkip to account menu

PA2G4 gene

Known as: proliferation-associated 2G4, PA2G4, ERBB3-BINDING PROTEIN 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor.
Human Bre1, an E3 ligase for H2B monoubiquitination, binds p53 and enhances activator-dependent transcription. Ebp1, an ErbB3… 
Highly Cited
2006
Highly Cited
2006
Nuclear Akt associates with PKC‐phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase‐activated DNase
Akt promotes cell survival through phosphorylation. The physiological functions of cytoplasmic Akt have been well defined, but… 
Highly Cited
2006
Highly Cited
2006
Ebp1 isoforms distinctively regulate cell survival and differentiation.
Ebp1, an ErbB3 receptor-binding protein, inhibits the proliferation and induces the differentiation of human cancer cells. Ebp1… 
Highly Cited
2006
Highly Cited
2006
Ebp1 is a dsRNA-binding protein associated with ribosomes that modulates eIF2alpha phosphorylation.
Highly Cited
2005
Highly Cited
2005
The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells.
Down-regulation of the androgen receptor (AR) is being evaluated as an effective therapy for the advanced stages of prostate… 
2004
2004
Heregulin Regulates the Ability of the ErbB3-binding Protein Ebp1 to Bind E2F Promoter Elements and Repress E2F-mediated Transcription*
The ErbB3/4 ligand heregulin (HRG) profoundly affects cell growth and differentiation, but its mechanism of action is poorly… 
2004
2004
Specificity and heregulin regulation of Ebp1 (ErbB3 binding protein 1) mediated repression of androgen receptor signalling
Although ErbB receptors have been implicated in the progression of prostate cancer, little is known about proteins that may… 
Highly Cited
2002
Highly Cited
2002
Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1
Members of the ErbB family of receptors have been implicated in regulation of androgen receptor (AR) activity. Ebp1, an ErbB-3… 
Highly Cited
2001
Highly Cited
2001
Ebp1, an ErbB‐3 binding protein, interacts with Rb and affects Rb transcriptional regulation
Ebp1, an ErbB‐3 binding protein, inhibits the proliferation and induces the differentiation of human breast cancer cells. The… 
Highly Cited
1997
Highly Cited
1997
Molecular cloning and mapping of a human cDNA (PA2G4) that encodes a protein highly homologous to the mouse cell cycle protein p38-2G4.
We have identified a novel human gene with strong homology to the mouse Pa2g4 cell cycle gene. This novel gene (called PA2G4… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)