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Oxyphenisatin Acetate

Known as: Acetfenolisatin, 2H-Indol-2-one, 3,3-bis(4-(acetyloxy)phenyl)-1,3-dihydro-, Diasatine 
A laxative that undergoes enterohepatic circulation. It may cause jaundice.
National Institutes of Health

Related topics

Related topics

11 relations

Broader (3)

CatharticsDioxyphenylisatinOxyphenisatin
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (1)

laxos

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Oxyphenisatin acetate (NSC 59687) triggers a cell starvation response leading to autophagy, mitochondrial dysfunction, and autocrine TNFα-mediated apoptosis
Oxyphenisatin (3,3‐bis(4‐hydroxyphenyl)‐1H‐indol‐2‐one) and several structurally related molecules have been shown to have in… 
2004
2004
Pathway of sodium moving from blood to intestinal lumen under the influence of oxyphenisatin and deoxycholate
Summary1.The transfer of 51CrEDTA and inulinsubstances which are distributed only in the extracellular space-across the rat… 
1977
1977
[Failure of oral contraception--probably because of interaction with phenemal].
A 30-year-old woman was using oral contraceptives (50 mcg ethinyl estradiol and 75 mcg Org. 2969) while simultaneously taking… 
1973
1973
Effect of the laxatives oxyphenisatine and oxyphenisatine acetate (diasatine) on the liver
1973
1973
["Fl. 1.75 at the drugstore"; chronic liver damage from oxyphenisatine (Diasatine)].
1972
1972
WITHDRAWAL OF OXYPHENISATIN ACETATE, DIACETOXYDIPHENOLISATIN AND TRIACETYLDIPHENOLISATIN FROM THE AUSTRALIAN MARKET
Attention was drawn to the suspected hepatotoxicity of oxyphenisatin and triacetyldiphenolisatin in May, 1971, with the… 
1971
1971
Jaundice due to oxyphenisatin.
1970
1970
Jaundice and oxyphenisatin.
  • G. McHardyL. Balart
  • Journal of the American Medical Association (JAMA…
  • 1970
  • Corpus ID: 8407746
Two middle-aged women were hospitalized with a similar, moderately severe illness consisting of fatigue, vague abdominal symptoms… 
1970
1970
Puzzling Jaundice: Probable Relationship to Laxative Ingestion
Four women, ages 47 to 86 years, had a similar, moderately severe illness characterized by fatigue, vague abdominal symptoms… 
1970
1970
Oxyphenisatin and jaundice.
  • K. Naess
  • Journal of the American Medical Association (JAMA…
  • 1970
  • Corpus ID: 43618648
To the Editor.— Your journal has recently presented two publications and one editorial concerning the "puzzling" jaundice seen… 
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