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Oxi8006

 
National Institutes of Health

Papers overview

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2015
2015
This study describes the vascular disrupting ability and the mechanism of action of the indole-based tubulin-binding compound… Expand
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2015
2015
Tubulin-binding, small-molecule vascular disrupting agents (VDAs) are anticancer agents that rapidly depolymerize microtubules… Expand
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2013
2013
The discovery of a 2-aryl-3-aroyl indole-based small-molecule inhibitor of tubulin assembly (referred to as OXi8006) inspired the… Expand
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2013
2013
The natural products colchicine and combretastatin A-4 are potent inhibitors of tubulin assembly, and they have inspired the… Expand
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