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Other cephalosporins and penems in ATC

Known as: Other cephalosporins and penems 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
5,5,6-Fused tricycles bearing imidazole and pyrazole 6-methylidene penems as broad-spectrum inhibitors of beta-lactamases.
2008
2008
Targeting Val 216 in Class A β‐Lactamases with Tricyclic 6‐Methylidene Penems
Recently, we reported on the discovery and biological activities of tricyclic 6-methylidene penems as mechanism-based inhibitors… 
2007
2007
On the Absolute Configuration in 1,4‐Dihydrothiazepine Covalent Complexes Derived from Inhibition of Class A and C β‐Lactamases with 6‐Methylidene Penems
Serine and metallo b-lactamases catalyze the hydrolysis of blactam rings in all classes of blactam antibiotics which is a major… 
2005
2005
Thiocarbonyl-based 1,3-dipolarophiles for the synthesis of C(2)-unsubstituted penems
Abstract The azomethine ylid strategy for β-lactam synthesis, which involves the fragmentation of a β-lactam-based oxazolidinone… 
2004
2004
In vitro and in vivo activities of novel 6-methylidene penems as beta-lactamase inhibitors.
Novel penem molecules with heterocycle substitutions at the 6 position via a methylidene linkage were investigated for their… 
2004
2004
S-alkyl dithioformates as 1,3-dipolarophiles. Generation of C(2)-unsubstituted penems.
S-Alkyl dithioformates, generated by a cycloreversion process, react as 1,3-dipolarophiles with beta-lactam-based azomethine… 
1998
1998
Preparation and antimicrobial assessment of 2-thioether-linked quinolonyl-carbapenems.
This reports the synthesis and in vitro antimicrobial properties of a series of 2-thioether-linked quinolonyl-carbapenems… 
1998
1998
Synthesis and antibacterial activity of 2-alkoxy penems.
1988
1988
Synthesis and biological activity of 2-lactonyl penems.
A series of potent antibacterial agents have been prepared. These agents are penems carrying a lactone ring in the C-2 position… 
1986
1986
2-(quaternary ammonio)-methyl penems.
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