Onercept
National Institutes of Health
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Opinion statementAnti-tumor necrosis factor-α (anti-TNF) therapy has become a very important modality in the treatment of…
The better understanding of the mechanisms of inflammatory bowel disease has driven our progress into the development of new…
ObjectiveTo develop a population pharmacokinetic model and to determine the covariates affecting the pharmacokinetics of onercept…
Inflammatory bowel disease (IBD) is a chronic immunoinflammatory response to an stimulus that activates a chain of cellular…
Inflammatory bowel diseases (IBD), namely ulcerative colitis (UC) and Crohn's disease (CD) are chronic disorders which appear to…
The introduction of infliximab, a mouse/human chimeric monoclonal antibody to tumor necrosis factor (TNF), is an important…
Onercept is a recombinant human soluble p55 tumor necrosis factor binding protein under development by Serono for the potential…
The safety, pharmacokinetics and pharmacodynamics of recombinant human tumour necrosis factor-binding protein-1 (r-hTBP-1…