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Oncolytic HSV1716
Known as:
HSV1716
A neuroattenuated, replication-restricted, ICP34.5 deleted (RL1 gene)-mutant herpes simplex virus (HSV) type I, constructed from wild-type strain 17…
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National Institutes of Health
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NCIt Antineoplastic Agent Terminology
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2016
2016
Oncolytic HSV1716 in combination with targeted anti cancer agents : identification of synergistic interactions and their mechanisms of synergy
L. Braidwood
2016
Corpus ID: 89768243
Oncolytic viruses are multifunctional cancer agents with huge clinical potential, and recently the first Herpes Simplex Virus…
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2010
2010
Abstract 2410: Development of a genetically-optimized whole tumor cell vaccine for ovarian cancer using HSV-derived glycoprotein D
A. Hagemann
,
Rachel Leskowitz
,
G. Cohen
,
G. Coukos
,
D. Powell
2010
Corpus ID: 71686346
Background: Dendritic cell (DC) vaccines offer a promising addition to standard treatment for ovarian cancer with surgery and…
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2006
2006
A phase 1 trial of the herpes simplex virus HSV1716 in patients with high grade glioma plus an in vitro investigation of the interaction between HSV1716 and ionising radiation
S. Harrow
2006
Corpus ID: 78397959
HSV1716 is a mutant herpes simplex virus with a deletion in both copies of the RL1 gene, that encodes the protein ICP34.5, a…
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2002
2002
Oral Presentations
E. Allan
,
S. Graham
,
+8 authors
M. Gore
British Journal of Cancer
2002
Corpus ID: 5578146
occurred. In the trial reported here, patients with high grade glioma had their tumours surgically resected and 10 pfu of the…
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