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Oligogenic Inheritance

Known as: Oligogenic Traits, Inheritance, Oligogenic, Oligogenic Inheritances 
A phenotypic outcome (physical characteristic or disease predisposition) that is determined by a few genes.
National Institutes of Health

Related topics

Related topics

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Broader (1)

Multifactorial Inheritance

Papers overview

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2008
2008
Empirical significance values for linkage analysis: trait simulation using posterior model distributions from MCMC oligogenic segregation analysis
Variance‐components (VC) linkage analysis is a powerful model‐free method for assessing linkage, but the distribution of VC… 
2005
2005
Corcoran Lecture. Cardiovascular genomics and oxidative stress.
The majority of modifiable cardiovascular risk factors are complex, polygenic, or at least oligogenic traits, with genetic and… 
Review
2004
Review
2004
Joint oligogenic segregation and linkage analysis using bayesian Markov chain Monte Carlo methods
One of the most challenging areas in human genetics is the dissection of quantitative traits. In this context, the efficient use… 
Review
2003
Review
2003
Familial neuroblastoma: a complex heritable disease.
2000
2000
A likelihood-based extended admixture model of oligogenic inheritance in ‘model-based’ and ‘model-free’ analysis
The admixture test of linkage heterogeneity is the most often and most successfully applied oligogenic-model linkage and/or LD… 
1998
1998
Replication Analysis of a Putative Susceptibility Locus (EGI) for Idiopathic Generalized Epilepsy on Chromosome 8q24
Summary: Purpose: The present replication study was designed to test the validity of a previously mapped susceptibility locus… 
1996
1996
A major gene for resting metabolic rate unassociated with body composition: results from the Québec Family Study.
A major gene hypothesis for resting metabolic rate (RMR) was investigated using segregation analysis (POINTER) of data on… 
1996
1996
Genetic pleiotropy for resting metabolic rate with fat-free mass and fat mass: the Québec Family Study.
Shared genetic and familial environmental causes for the associations among resting metabolic rate (RMR), fat-free mass (FFM… 
1995
1995
Genetic analysis of a common oligogenic trait with quantitative correlates: Summary of GAW9 results
The statistical genetic analyses of a simulated data set for Genetic Analysis Workshop 9 Problem 2 are summarized. A diverse set… 
1995
1995
Screening a 2 cM genetic map for allelic association: A simulated oligogenic trait
In this paper, we explore the use of a variety of familial transmission tests (and case‐control analyses) to screen for allelic… 
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