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Octamer Transcription Factors

Known as: Oct Proteins, Octamer Transcription Factors [Chemical/Ingredient], Transcription Factors, Octamer 
A family of POU domain factors that bind the octamer motif ATTTGCAT in enhancer and PROMOTER REGIONS to regulate GENE EXPRESSION.
National Institutes of Health

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Pou2f3 protein, mouse

Papers overview

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2001
2001
Octamer Transcription Factors Up-regulate the Expression of CCR5, a Coreceptor for HIV-1 Entry*
T cell activation can induce expression of CCR5, a major coreceptor for macrophage-tropic (R5) human immunodeficiency virus type… Expand
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Highly Cited
2000
Highly Cited
2000
PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene*
  • Michael Rehli, A. Poltorak, Lucia Schwarzfischer, S. Krause, Reinhard Andreesen, Bruce Beutler
  • The Journal of Biological Chemistry
  • 2000
    • Corpus ID: 22078217
The protein product of the Toll-like receptor (TLR) 4 gene has been implicated in the signal transduction events induced by… Expand
Highly Cited
1999
Highly Cited
1999
Selective Binding of Steroid Hormone Receptors to Octamer Transcription Factors Determines Transcriptional Synergism at the Mouse Mammary Tumor Virus Promoter*
Transcriptional synergism between glucocorticoid receptor (GR) and octamer transcription factors 1 and 2 (Oct-1 and Oct-2) in the… Expand
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Highly Cited
1998
Highly Cited
1998
Recruitment of Octamer Transcription Factors to DNA by Glucocorticoid Receptor
ABSTRACT Glucocorticoid receptor (GR) and octamer transcription factors 1 and 2 (Oct-1/2) interact synergistically to activate… Expand
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Highly Cited
1997
Highly Cited
1997
The Cyclin-dependent Kinase-activating Kinase (CAK) Assembly Factor, MAT1, Targets and Enhances CAK Activity on the POU Domains of Octamer Transcription Factors*
Octamer binding transcription factors (Oct factors) play important roles in activation of transcription of various genes but, in… Expand
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Highly Cited
1995
Highly Cited
1995
High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.
The octamer transcription factors Oct1 and Oct2 are involved in the transcriptional regulation of both lymphoid‐specific and… Expand
Highly Cited
1991
Highly Cited
1991
Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome.
Chromosomal locations have been assigned for the octamer transcription factor, Otf, gene family (previously named the octamer… Expand
Review
1990
Review
1990
Octamer transcription factors and the cell type‐specificity of immunoglobulin gene expression
Antibodies are produced exclusively in B lymphocytes. The expression of the antibody‐encoding genes, the immunoglobulin (Ig… Expand
Highly Cited
1989
Highly Cited
1989
Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoter.
All promoters of immunoglobulin heavy chain genes contain three conserved sequence motifs: a heptamer motif CTCATGA, an octamer… Expand
Highly Cited
1989
Highly Cited
1989
Octamer transcription factors 1 and 2 each bind to two different functional elements in the immunoglobulin heavy-chain promoter.
Immunoglobulin heavy-chain genes contain two conserved sequence elements 5' to the site of transcription initiation: the octamer… Expand
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