OXGR1 gene

Obesity is associated with macrophage infiltration and metabolic inflammation, both of which promote metabolic disease… (More)

OBJECTIVE The cysteinyl leukotrienes (CysLTs) are lipid mediators that have been implicated in the pathogenesis of allergic… (More)

Cysteinyl leukotrienes (cysLTs), leukotriene C4 (LTC4), LTD4, and LTE4 are proinflammatory lipid mediators with pathobiologic… (More)

The G-protein-coupled receptors (GPCRs) family of proteins play essential roles in the heart, including in the regulation of… (More)

BACKGROUND Mast cells derived from human lungs (HLMCs) express multiple G-protein coupled purinergic receptors (P2YR) and the so… (More)

The cysteinyl leukotrienes (cys-LTs), leukotriene C4 (LTC4), a conjugation product of glutathione and eicosatetraenoic acid, and… (More)

The citric acid cycle is central to the regulation of energy homeostasis and cell metabolism. Mutations in enzymes that catalyse… (More)

AMP and adenosine are found in all cell types and can be released by cells or created extracellularly from the breakdown of ATP… (More)

The orphan receptor GPR80 (also called GPR99) was recently reported to be the P2Y15 receptor activated by AMP and adenosine and… (More)

Based on sequence similarity, the superfamily of G protein-coupled receptors (GPRs) can be subdivided into several subfamilies… (More)