OSI-7904L

Known as: GS7904L, OSI 7904L, OSI-7904 liposomal 
A liposome-encapsulated formulation of the benzoquinazoline folate analog OSI-7904 with antineoplastic activity. As a thymidylate synthase inhibitor… (More)
National Institutes of Health

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2009
2009
e17005 Background: Given the limited efficacy and relative toxicity of chemotherapy for metastatic or recurrent squamous cell… (More)
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2008
2008
PURPOSE To evaluate the safety and describe the pharmacokinetic profile of OSI-7904L, a novel liposomal thymidylate synthase… (More)
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2007
2007
PurposeOSI-7904L is a liposomal formulation of a potent thymidylate synthase (TS) inhibitor. This phase I study evaluated the… (More)
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2007
2007
SummaryThe prognosis of advanced biliary tract carcinoma is poor with chemotherapy limited to a palliative role. This randomised… (More)
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2006
2006
A two-stage Simon design was used to evaluate the response rate of OSI-7904L, a liposome encapsulated thymidylate synthase… (More)
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2005
2005
PURPOSE OSI-7904L is a liposomal formulation of a potent noncompetitive thymidylate synthase inhibitor (TSI) that does not… (More)
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2005
2005
4042 Background: OSI-7904L is a liposomal TS inhibitor with increased plasma residence and superior preclinical antitumor… (More)
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2004
2004
OSI-7904L [(S)-2-[5-[(1,2-dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino-1-oxo-2-isoindolynl]-glutaric acid] is a… (More)
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1994
1994
Wie bereits im vorangegangenen Kapitel dargestellt, zielt die internationale Standardisierung im Bereich der systemtechnischen… (More)
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