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OSBPL8 gene

Known as: MST120, OXYSTEROL-BINDING PROTEIN-LIKE PROTEIN 8, OSBP-RELATED PROTEIN 8 
National Institutes of Health

Related topics

Related topics

1 relation
OSBPL1A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
ORP5 and ORP8: Sterol Sensors and Phospholipid Transfer Proteins at Membrane Contact Sites?
Oxysterol binding related proteins 5 and 8 (ORP5 and ORP8) are two close homologs of the larger oxysterol binding protein (OSBP… 
2019
2019
Targeting plasma membrane phosphatidylserine content to inhibit oncogenic KRAS function
KRAS-dependent cancer cell growth is inhibited by disrupting phosphatidylserine transport to the plasma membrane by genetic… 
Highly Cited
2018
Highly Cited
2018
PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) is a critically important regulatory lipid of the plasma membrane (PM); however… 
2018
2018
Rs4705342 polymorphism is involved in the tumorigenesis of HBV positive HCC by altering the binding affinity of HBV induced NF‐kB with the promoter region of microRNA‐143
The objective of this study was to explore the role of rs4705342 located in the miR‐143 promoter in relation to the control of… 
Highly Cited
2017
Highly Cited
2017
ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P2) and regulate its level at the plasma membrane
ORP5 and ORP8, members of the oxysterol-binding protein (OSBP)-related proteins (ORP) family, are endoplasmic reticulum membrane… 
2016
2016
Oxysterol binding protein-related protein 8 mediates the cytotoxicity of 25-hydroxycholesterol[S]
Oxysterols are 27-carbon oxidized derivatives of cholesterol or by-products of cholesterol biosynthesis that can induce cell… 
2015
2015
Oxysterol-binding Protein-related Protein 8 (ORP8) Increases Sensitivity of Hepatocellular Carcinoma Cells to Fas-Mediated Apoptosis*
Background: The mechanism of HCC resistant to Fas-mediated apoptosis is not clearly understood. Results: ORP8 triggered HCC cell… 
Highly Cited
2014
Highly Cited
2014
Genome Wide Association Study Identifies 20 Novel Promising Genes Associated with Milk Fatty Acid Traits in Chinese Holstein
Detecting genes associated with milk fat composition could provide valuable insights into the complex genetic networks of genes… 
2014
2014
Orp8 Deficiency in Bone Marrow-Derived Cells Reduces Atherosclerotic Lesion Progression in LDL Receptor Knockout Mice
Introduction Oxysterol binding protein Related Proteins (ORPs) mediate intracellular lipid transport and homeostatic regulation… 
2012
2012
OSBP-Related Proteins (ORPs) in Human Adipose Depots and Cultured Adipocytes: Evidence for Impacts on the Adipocyte Phenotype
Oxysterol-binding protein (OSBP) homologues, ORPs, are implicated in lipid homeostatic control, vesicle transport, and cell… 
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