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ORG 21465

Known as: ORG-21465 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2002
012319972002

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2002
2002
Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo.
The objective of the present investigation was to characterize the in vivo EEG effects of (synthetic) neuroactive steroids on the… (More)
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1998
1998
Pharmacological modulation of GABA(A) receptor-mediated postsynaptic potentials in the CA1 region of the rat hippocampus.
It is unclear whether GABA(A) receptor-mediated hyperpolarizing and depolarizing synaptic potentials (IPSP(A)s and DPSP(A)s… (More)
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1997
1997
Computer-controlled infusion of ORG 21465, a water soluble steroid i.v. anaesthetic agent, into human volunteers.
ORG 21465 has been found to possess anaesthetic properties in humans and its pharmacokinetics are known. We performed this study… (More)
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1997
1997
Administration to humans of ORG 21465, a water soluble steroid i.v. anaesthetic agent.
Ten male volunteers received a 1-min i.v. infusion of a new water soluble steroid anaesthetic agent, ORG 21465. Individuals… (More)
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Review
1997
Review
1997
ORG 21465, a new water-soluble steroid hypnotic: more of the same or something different?
ORG 21465, a new water-soluble steroid hypnotic: more of the same or something different? The first demonstration of the… (More)
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