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ONO-6950
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
gemilukast
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A new CysLT1 and CysLT2 receptors-mediated anaphylaxis guinea pig model.
Tomohiko Sekioka
,
Michiaki Kadode
,
+6 authors
Kazuhito Kawabata
Prostaglandins, leukotrienes, and essential fatty…
2017
Although the effectiveness of CysLT1 receptor antagonists on asthma has been clinically established, the effects of CysLT2…
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2016
2016
A dual CysLT1/2 antagonist attenuates allergen-induced airway responses in subjects with mild allergic asthma.
Gail M Gauvreau
,
Louis-Philippe Boulet
,
+7 authors
Paul M. O'Byrne
Allergy
2016
BACKGROUND The cysteinyl leukotrienes (cysLTs) play a key role in the pathophysiology of asthma. In addition to functioning as…
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2015
2015
Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a guinea pig model of asthma.
Yasuo Yonetomi
,
Tomohiko Sekioka
,
+11 authors
Kazuhito Kawabata
European journal of pharmacology
2015
We assessed in this study the anti-asthmatic effects of ONO-6950, a novel cysteinyl leukotriene 1 (CysLT1) and 2 (CysLT2…
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2015
2015
Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction.
Tomohiko Sekioka
,
Michiaki Kadode
,
+5 authors
Takeshi Nabe
Allergology international : official journal of…
2015
BACKGROUND The expression and functional role of CysLT2 receptors in asthma have not been clarified. In this study, we evaluated…
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2015
2015
Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma.
Satoshi Itadani
,
Kentaro Yashiro
,
+26 authors
Kazuyuki Ohmoto
Journal of medicinal chemistry
2015
An orally active dual CysLT1 and CysLT2 antagonist possessing a distinctive structure which consists of triple bond and…
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2014
2014
Late-breaking abstract: Effects of a dual CysLT1/2 antagonist, ONO-6950, on allergen-induced airway responses in subjects with mild allergic asthma
Gail M Gauvreau
,
Louis-Philippe Boulet
,
+8 authors
Paul M O'Byrne
2014
Background: The cysteinyl leukotrienes (CysLTs) play a key role in the pathophysiology of asthma. In addition to functioning as…
Expand
Is this relevant?