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ON 01910

Known as: ON-01910, ON01910 
National Institutes of Health

Papers overview

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2019
2019
Purpose: Squamous cell carcinoma (SCC) of the skin is the leading cause of death in patients with the severe generalized form of… 
2018
2018
Inhibition of RAS-RAF-ERK-signaling is a major mechanism mediated by the multi-kinase inhibitors sorafenib and regorafenib, the… 
2014
2014
ON01910.Na is a highly effective anticancer agent that induces mitotic arrest and apoptosis. Clinical studies with ON01910 in… 
2013
2013
Polo-like kinase 1 (PLK1), one of the key regulators of mitosis, is a target for cancer therapy due to its abnormally high… 
2012
2012
ABSTRACTPurposeTo evaluate a mitotic inhibitor, ON01910.Na, as a potential chemotherapeutic agent for brain tumors using a series… 
2010
2010
During the preclinical drug discovery process it remains a challenge to enable early elimination of candidate molecules that may… 
Review
2010
Review
2010
IntroductionOvarian cancer is a difficult to treat cancer entity with a high relapse rate. After initial surgery and chemotherapy… 
Review
2009
Review
2009
Purpose:Antimitotic chemotherapy remains a cornerstone of multimodality treatment for locally advanced andmetastatic cancers.To…