OC000459

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2012-2018
012320122018

Papers overview

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2018
2018
The role of leukotrienes and prostaglandins in development of atopy has been prototypically established in studies of asthma… (More)
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Review
2016
Review
2016
INTRODUCTION By activating DP1 and DP2 receptors on immune and non-immune cells, prostaglandin D2 (PGD2), a major metabolic… (More)
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Review
2015
Review
2015
  • R A Mcivor
  • Annals of allergy, asthma & immunology : official…
  • 2015
OBJECTIVE Asthma is a chronic inflammatory disorder of the airways with increasing worldwide prevalence. Despite treatment… (More)
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2014
2014
BACKGROUND The CRTH2 antagonist OC000459 has previously been demonstrated to reduce airway inflammation and improve lung function… (More)
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2013
2013
BACKGROUND Eosinophilic esophagitis (EoE) is a chronic, Th2-type inflammatory disease. Chemoattractant receptor-homologous… (More)
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2013
2013
CRTH2 (chemoattractant receptor expressed on T-helper (Th) type 2 cells) is a G-protein-coupled receptor expressed by Th2… (More)
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2013
2013
n engl j med 368;26 nejm.org june 27, 2013 2513 3. Nair P, Gaga M, Zervas E, et al. Safety and efficacy of a CXCR2 antagonist in… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND CRTH2 is a G-protein-coupled receptor that mediates the activation of Th2 lymphocytes, eosinophils and basophils in… (More)
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2012
2012
BACKGROUND CRTH2 mediates activation of Th2 cells, eosinophils and basophils in response to prostaglandin D(2). The CRTH2… (More)
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2012
2012
D prostanoid receptor 2 (DP₂) [also known as chemoattractant receptor-homologous molecule expressed on T helper 2 (Th2) cells… (More)
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