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OC000459

 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
The role of leukotrienes and prostaglandins in development of atopy has been prototypically established in studies of asthma… Expand
Review
2017
Review
2017
Prostaglandin D2 (PGD2) released by degranulating mast cells is believed to play a key role in orchestrating mechanisms of… Expand
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Highly Cited
2014
Highly Cited
2014
The CRTH2 antagonist OC000459 has previously been demonstrated to reduce airway inflammation and improve lung function in… Expand
Highly Cited
2013
Highly Cited
2013
Eosinophilic esophagitis (EoE) is a chronic, Th2‐type inflammatory disease. Chemoattractant receptor‐homologous molecule on Th2… Expand
2013
2013
  • I. Hughes
  • The New England journal of medicine
  • 2013
  • Corpus ID: 31941319
What is so magical about the age at onset of puberty in humans — currently set at approximately 11 years of age?1 Why not 6 or 16… Expand
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Highly Cited
2012
Highly Cited
2012
Background CRTH2 is a G‐protein‐coupled receptor that mediates the activation of Th2 lymphocytes, eosinophils and basophils in… Expand
Highly Cited
2012
Highly Cited
2012
CRTH2 (chemoattractant receptor expressed on T-helper (Th) type 2 cells) is a G-protein-coupled receptor expressed by Th2… Expand
Highly Cited
2012
Highly Cited
2012
CRTH2 mediates activation of Th2 cells, eosinophils and basophils in response to prostaglandin D2. The CRTH2 antagonist OC000459… Expand
2012
2012
D prostanoid receptor 2 (DP2) [also known as chemoattractant receptor-homologous molecule expressed on T helper 2 (Th2) cells… Expand
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2012
2012
bent position for 30 min with one of the following saline solutions at pH 7.2, 1.0 and 5.0. Thereafter, recording continued for… Expand