Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

OC000459

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The role of leukotrienes and prostaglandins in development of atopy has been prototypically established in studies of asthma… Expand
Is this relevant?
Review
2017
Review
2017
Prostaglandin D2 (PGD2) released by degranulating mast cells is believed to play a key role in orchestrating mechanisms of… Expand
  • table 1
  • table 2
  • table 2
  • figure 1
Is this relevant?
Highly Cited
2014
Highly Cited
2014
BACKGROUND The CRTH2 antagonist OC000459 has previously been demonstrated to reduce airway inflammation and improve lung function… Expand
Is this relevant?
2014
2014
1 Atopix Therapeutics Ltd, The Innovation Centre, 99 Park Drive, Milton Park, Abingdon, UK | 2TLWise Consulting, Cambridge, UK… Expand
Is this relevant?
Highly Cited
2013
Highly Cited
2013
BACKGROUND Eosinophilic esophagitis (EoE) is a chronic, Th2-type inflammatory disease. Chemoattractant receptor-homologous… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • table 2
Is this relevant?
2013
2013
CRTH2 (chemoattractant receptor expressed on T-helper (Th) type 2 cells) is a G-protein-coupled receptor expressed by Th2… Expand
Is this relevant?
2013
2013
What is so magical about the age at onset of puberty in humans — currently set at approximately 11 years of age?1 Why not 6 or 16… Expand
  • figure 1
Is this relevant?
Highly Cited
2012
Highly Cited
2012
BACKGROUND CRTH2 is a G-protein-coupled receptor that mediates the activation of Th2 lymphocytes, eosinophils and basophils in… Expand
Is this relevant?
2012
2012
BACKGROUND CRTH2 mediates activation of Th2 cells, eosinophils and basophils in response to prostaglandin D(2). The CRTH2… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
2012
2012
D prostanoid receptor 2 (DP₂) [also known as chemoattractant receptor-homologous molecule expressed on T helper 2 (Th2) cells… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • table 2
Is this relevant?