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Nucleoside Reverse Transcriptase Inhibitor

Known as: NRTI, Nucleoside Analog Reverse Transcriptase Inhibitor 
A substance with a structure similar to a nucleoside molecule that is capable of occupying the active catalytic site of a reverse transcriptase… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND The non-nucleoside reverse transcriptase inhibitor (NNRTI), rilpivirine (TMC278; Tibotec Pharmaceuticals, County Cork… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Over 150,000 Malawians have started antiretroviral therapy (ART), in which first-line therapy is stavudine/lamivudine… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The metabolic effects of initial therapy for HIV-1 infection are important determinants of regimen selection… Expand
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Highly Cited
2008
Highly Cited
2008
OBJECTIVES The aim of this study was to investigate the frequency of CYP2B6 polymorphisms (according to ethnicity) and the… Expand
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Review
2007
Review
2007
OBJECTIVES Monitoring regional levels of transmitted HIV-1 resistance informs treatment guidelines and provides feedback on the… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To estimate insulin resistance and its relationship to antiretroviral therapy (ART) in a cohort of HIV-infected persons… Expand
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Highly Cited
2004
Highly Cited
2004
Anti-AIDS drug candidate and non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC125-R165335 (etravirine) caused an initial… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE To determine the prevalence of risk factors for cardiovascular disease (CVD) among HIV-infected persons, and to… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Lipodystrophy (LD; peripheral lipoatrophy, central adiposity) hyperlipidaemia and insulin resistance often complicate… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Progressive subcutaneous fat wasting, fat accumulation, dyslipidaemia and insulin resistance in HIV-infected patients… Expand
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