Nuclear Matrix

Known as: Nuclear Scaffolds, Nucleoskeleton, Nucleoskeletons 
The residual framework structure of the CELL NUCLEUS that maintains many of the overall architectural features of the cell nucleus including the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1959-2017
05010015019592017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
BRCA2 mutations predispose carriers to breast and ovarian cancer and can also cause other cancers and Fanconi anemia. BRCA2 acts… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The Wnt-responsive transcription factor LEF1 can activate transcription in association with beta-catenin and repress… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
We report here that living cells and nuclei are hard-wired such that a mechanical tug on cell surface receptors can immediately… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Spinocerebellar ataxia type 1 (SCA1) is one of several neurodegenerative disorders caused by an expansion of a polyglutamine… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1992
Highly Cited
1992
This report shows that human telomeres are tightly associated with the nuclear matrix. Telomere attachment is observed in several… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Matrix attachment regions (MARs) are thought to separate chromatin into topologically constrained loop domains. A MAR located 5… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
The nuclear matrix is concealed by a much larger mass of chromatin, which can be removed selectively by digesting nuclei with… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1984
Highly Cited
1984
Madin-Darby canine kidney (MDCK) cells grow as differentiated, epithelial colonies that display tissue-like organization. We… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1982
Highly Cited
1982
The structural filament network of the nucleus is prepared while still connected to the cytoskeleton. The relatively gentle… (More)
Is this relevant?
Highly Cited
1977
Highly Cited
1977
A nuclear framework structure termed the nuclear matrix has been isolated and characterized. This matrix forms the major residual… (More)
  • table I
  • table II
  • table III
  • figure 1
  • figure 2
Is this relevant?