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Notch Signaling Inhibitor PF-06650808
Known as:
PF-06650808
National Institutes of Health
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2015
2015
30LBA A Phase 1 dose escalation, safety, and pharmacokinetic study of PF-06650808, an anti-Notch3 antibody drug conjugate, in adult patients with advanced solid tumors
L. Rosen
,
R. Wesolowski
,
+7 authors
A. Tolcher
2015
Corpus ID: 79007167
2015
2015
Abstract 1697: Therapeutic targeting the NOTCH3 receptor with antibody drug conjugates
K. Geles
,
Yijie Gao
,
+14 authors
P. Sapra
Experimental and Molecular Therapeutics
2015
Corpus ID: 57496375
Activation and mutation of the NOTCH signaling pathway is oncogenic in many tissue types and the target of multiple anti-cancer…
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